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Bioimpacts. 2011;1(4): 199-201.
doi: 10.5681/bi.2011.028
PMID: 23678428
PMCID: PMC3648969
Scopus ID: 84876726247
  Abstract View: 2074
  PDF Download: 1043

Editorial

CNT Nanobombs for Specific Eradication of Cancer Cells: A New Concept in Cancer Theranostics

Yadollah Omidi 1,2* ORCID logo

1 Ovarian Cancer Research Center, School of Medicine, University of Pennsylvania, Philadelphia, USA
2 Research Center for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
*Corresponding Author: Email: yomidi@mail.med.upenn.edu

Abstract

Whole extermination of cancerous cells/tissue seems no longer to be a dream. Exploiting advanced photoactive nanomaterials such as functionalized fullerenes and carbon nanotubes (CNTs) can act as CNT nanobombs (CNT-NBs) when exposed to the near infrared (NIR) radiation. PEGylated CNTs tagged with an antibody/aptamer can target cancer cells. Once attached to cancer cells, the NIR emission (700-1100 nm), in which body tissues are mostly transparent, can be applied to CNT-NBs which can absorb the light and get heated up. The resultant enhanced temperature can abolish the cancer. Once stealth CNT-NBs are tagged with imaging moieties, it would be a matter of computer gaming for physician who can inject it for real time visualization and destruction of cancer by activation of the NIR laser. While, many nanosystems (NSs) are still in waiting list for clinical translation, our dreams may come true by applying stealth CNT-NBs against cancer.
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Submitted: 10 Oct 2011
Accepted: 15 Oct 2011
ePublished: 09 Nov 2011
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