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Bioimpacts. 2015;5(4): 177-182. doi: 10.15171/bi.2015.26
PMID: 26929921        PMCID: PMC4769787

Original Research

Effects of folic acid supplementation on serum homocysteine and lipoprotein (a) levels during pregnancy

Zohreh Hekmati Azar Mehrabani 1, Amir Ghorbanihaghjo 2, Manizheh Sayyah Melli 3, Maryam Hamzeh-Mivehroud 4, Nazila Fathi Maroufi 1, Nasrin Bargahi 4, Maryam Bannazadeh Amirkhiz 2, Nadereh Rashtchizadeh 2 *

Cited by CrossRef: 8


1- Cornet D, Clement A, Clement P, Menezo Y. High doses of folic acid induce a pseudo-methylenetetrahydrofolate syndrome. SAGE Open Medical Case Reports. 2019;7:2050313X1985043 [Crossref]
2- Liu H, Li Q, Liu T, Tang Y, Yu F. Trimester-specific reference intervals of serum homocysteine levels for pregnant women: a longitudinal study in China. Gynecological Endocrinology. 2023;39(1) [Crossref]
3- Nozari S, Fathi Maroufi N, Nouri M, Paytakhti Oskouei M, Shiralizade J, Yekani F, Mamipour M, Faridvand Y. Decreasing serum homocysteine and hypocholesterolemic effects of bovine lactoferrin in male rat fed with high-cholesterol diet. J Cardiovasc Thorac Res. 2018;10(4):203 [Crossref]
4- Yang Y, Jiang H, Tang A, Xiang Z. Changes of serum homocysteine levels during pregnancy and the establishment of reference intervals in pregnant Chinese women. Clinica Chimica Acta. 2019;489:1 [Crossref]
5- Hou J, Lin L, Guo W, Luo D, Lan L. Association of methylenetetrahydrofolate reductase C677T polymorphism with the pre-eclampsia risk in Hakka pregnant women in Southern China. Gynecological Endocrinology. 2020;36(4):322 [Crossref]
6- Carletti J, Correia-Branco A, Silva C, Andrade N, Silva L, Martel F. The effect of oxidative stress induced by tert-butylhydroperoxide under distinct folic acid conditions: An in vitro study using cultured human trophoblast-derived cells. Reproductive Toxicology. 2018;77:33 [Crossref]
7- Shiralizadeh J, Barmaki H, Haiaty S, Faridvand Y, Mostafazadeh M, Mokarizadeh N, Kamrani A, Isazadeh A, Maroufi N. The effects of high and low doses of folic acid on oxidation of protein levels during pregnancy: a randomized double-blind clinical trial. 2018;33(3) [Crossref]
8- Chen C, Lu M, Zhang Z, Qin L. The role of lactoferrin in atherosclerosis. Biometals. 2023;36(3):509 [Crossref]


As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge