Bioimpacts. 2015;5(3):123-127.
doi: 10.15171/bi.2015.20
PMID: 26457249
PMCID: PMC4597159
Scopus id: 84944393625
  Abstract View: 414
  PDF Download: 313

Perspective

Reliability of malondialdehyde as a biomarker of oxidative stress in psychological disorders

Khalil Ansarin 1, Maryam Khoubnasabjafari 1, Abolghasem Jouyban 2 *

1 Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2 Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran

Article

Despite very wide variations of malondialdehyde (MDA) concentrations in biological samples, it is still used as a biomarker of oxidative stress in clinical investigations. In the current perspective study, we aimed to summarize a number of critical analytical points for determination of MDA. Technical problems and controversial findings in healthy people and some psychiatric disorders reveal that the reliability of MDA as a biomarker of oxidative stress needs to be re-evaluated by experts.
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Submitted: 11 Jun 2015
First published online: 23 Aug 2017
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