Tabriz University of Medical Sciences BioImpacts 2228-5652 6 3 2016 09 30 Tips on ligand immobilization and kinetic study using surface plasmon resonance 117 118 10.15171/bi.2016.17 EN Jafar Ezzati Nazhad Dolatabadi Miguel De la Guardia EDITORIAL 10.15171/bi.2016.17 2016 08 30 2016 09 25 Surface plasmon resonance (SPR) technique offers a robust label-free approach applicable in various investigations including binding affinity, specificity and kinetics of biological macromolecules (e.g., peptides, proteins and nucleotidase) and small molecules. SPR provides extremely important data on the kinetics and affinity of substances examined, through which bio-specific interaction(s) can be established by the analysis of adsorption of analyte onto the immobilized ligand(s) on a sensor-based analytical system. Due to SPR wide applications in biomedical laboratories, the aim of this editorial is to highlight the importance of SPR in affinity kinetics and ligand immobilization.