Bioimpacts. 2014;4(2):83-88.
doi: 10.5681/bi.2014.007
PMID: 25035851
PMCID: PMC4097976
Scopus id: 84905465316
  Abstract View: 679
  PDF Download: 489

Original Research

Effects of probiotic yogurt consumption on inflammatory biomarkers in patients with type 2 diabetes

Majid Mohammad-Shahi 1, Masoud Veissi 2, Fatemeh Haidari 2, Hajieh Shahbazian 3, Gholam-Abas Kaydani 4, Fatemeh Mohammadi 3 *

1 Hyperlipidemia Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2 Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
3 Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
4 Department of Laboratory Sciences, School of Para-medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Article

Introduction: The role of inflammatory cytokines in diabetes and its complications has been shown in some studies. The purpose of this study was to compare the effect of probiotic and conventional yogurt on inflammatory markers in patients with type 2 diabetes.
Methods: Forty- four patients with type 2 diabetes were participated in this randomized, double – blind controlled clinical trial and were assigned to two intervention and control groups. The subjects in the intervention group consumed 300 g/d probiotic yogurt and subjects in the control group consumed 300g/d conventional yogurt for 8 weeks. Anthropometric indices, dietary intakes, and serum levels of glucose, HbA1c, IL-6, TNF-α and hs-CRP were evaluated at the beginning and end of the intervention.
Results: For anthropometric indices and dietary intakes, no significant differences were seen within and between groups post intervention (p> 0.05). The consumption of probiotic yogurt caused significant decrease in HbA1c and TNF-α levels (p=0.032 and p= 0.040, respectively) in the intervention group.
Conclusions: It is suggested that probiotic yogurt may be used as an alternative prevention approach and treatment method to control diabetic complications.
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Submitted: 03 Dec 2013
First published online: 16 Aug 2017
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