Laya Farzadi
1, Esmat Aghadavod
2,4*, Mohammad Nouri
2*, Morteza Ghojazadeh
3, Mona Mohiti
31 Women Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2 Department of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
3 Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
4 Students’ Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract
Introduction:
Ovarian reserve depends on the size and quality of oocytes stored in
ovary. Aging and some diseases reduce ovarian reserve, leading to
decreased reproductive performance. Laparoscopic surgery is used to
treat infertility in women with PCOS. The purpose of this study was
measurement of ovarian reserve in patients with PCOS before and after
laparoscopic surgery. Methods: In this study
thirty infertile patients with PCOS that had not responded to initial
treatment with drug were selected. We assessed the serum levels of
anti-mullerian hormone, testosterone, luteinizing hormone (LH), and the
number of antral follicles before laparoscopic surgery and 1 week, 3 and
6 months after the surgery. Results: The
average amount of anti-mullerian hormone serum levels was 8.4±4.7 before
laparoscopic surgery and 7.5±4.5, 7±4.5, and 7.7±4.4 ng/ml one week, 3
and 6 months after surgery, respectively. Serum levels of LH was
13.6±6.7 and 12.7±11.1 IU /ml (P=0.87) before surgery and 6 months after
laparoscopy, respectively. Mean serum testosterone levels were 0.9±0.8,
0.8±0.9 ng/ml (P=0.86) before and after surgery. Annual reproductive
rate was 26.7 percent in this population. Conclusion:
Laparoscopic ovarian puncture didn’t change anti-mullerian hormone
serum, testosterone and LH in women with PCOS and hence has no adverse
effects on the ovarian reserve.