Logo-bi
Bioimpacts. 2011;1(3): 145-147.
doi: 10.5681/bi.2011.019
PMID: 23678419
PMCID: PMC3648960
Scopus ID: 84865491877
  Abstract View: 2541
  PDF Download: 1434

Editorial

Smart Multifunctional Theranostics: Simultaneous Diagnosis and Therapy of Cancer

Yadollah Omidi 1,2* ORCID logo

1 Ovarian Cancer Research Center, School of Medicine, University of Pennsylvania, Philadelphia, USA
2 Research Center for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
*Corresponding Author: Email: yomidi@mail.med.upenn.edu

Abstract

Clinical applications of advanced nanomedicines such as PEGylated liposomal doxorubicin and paclitaxel-albumin bioconjugates have significantly improved the cancer treatment strategies. However, these pharmaceuticals lack early detection and single cell tracking capabilities. Thus, engineering of smart multifunctional theranostics appear to be our next stepfor simultaneous diagnosis and therapy of cancer. Clinical translation of multifunctional theranostics appears to be dependent upon specificity of cancer biomarkers, biocompatibility of components used for formulation, and advancement of bioconjugation techniques. While many cancer biomarker candidates often fail to be used for clinical diagnosis/therapy because of their nonspecific functional expression in normal tissues, biocompatibility of materials used for bioconjugationalso needs to be approved.  All these issues need to be fully addressed prior to the translation of smart multifunctional cancer theranostics.
First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 2542

Your browser does not support the canvas element.


PDF Download: 1434

Your browser does not support the canvas element.

Submitted: 10 Sep 2011
Accepted: 15 Sep 2011
ePublished: 30 Sep 2011
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)