Logo-bi
Bioimpacts. 2024;14(6): 27691.
doi: 10.34172/bi.2024.27691
  Abstract View: 553
  PDF Download: 376

Perspective

Abuse potential of fentanyl and fentanyl analogues

Anusha Thumma 1 ORCID logo, Kwadwo Mfoafo 1, Niloofar Babanejad 2, Alborz Omidian 2, Yadollah Omidi 1, Hamid Omidian 1* ORCID logo

1 College of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL, United States
2 Westchester Medical Center, Department of Psychiatry, Valhalla, NY, United States
*Corresponding Author: Hamid Omidian‎, Email: omidian@nova.edu

Abstract

Introduction: In this perspective review, we evaluated the clinical management of fatal fentanyl overdose in several routes of administration, concentrating on both legally prescribed and illegally produced formulations.
Methods: A literature search was conducted on Web of Science, PubMed, and Google Scholar databases, using the following keywords: fentanyl, illicit fentanyl, deaths, misuse, abuse, and naloxone. We included only articles whose abstracts were available in English. All articles were screened using their abstracts to determine their relevance to the current review.
Results: The gold standard for treating both acute and chronic pain is fentanyl, but abuse of the drug has exploded globally since the late 2000s. Fentanyl abuse has been shown to frequently result in serious harm and even death.
Conclusions: By educating patients and physicians, making rescue kits easily accessible, developing vaccines to prevent opioid addiction, and perhaps even creating new tamper-resistant fentanyl formulations, it may be possible to prevent fentanyl misuse, therapeutic errors, and the repercussions that follow.
First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 553

Your browser does not support the canvas element.


PDF Download: 376

Your browser does not support the canvas element.

Submitted: 12 Nov 2022
Revision: 02 Feb 2024
Accepted: 05 Mar 2024
ePublished: 18 Mar 2024
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)