Bioimpacts. 2024;14(3): 29945.
doi: 10.34172/bi.2023.29945
  Abstract View: 95
  PDF Download: 388


Regulation of cell fate by cell imprinting approach in vitro

Farkhonde Hasannejad 1,2 ORCID logo, Leila Montazeri 3, João F Mano 4* ORCID logo, Shahin Bonakdar 5* ORCID logo, Ahmad ‎ Fazilat 2

1 Department of Tissue Engineering and Applied Cell Sciences, School of Medicine, Semnan ‎University of Medical Science, Semnan, Iran
2 Genetic Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, ‎Tehran, Iran
3 Department of Cell Engineering, Cell Science Research Center, Royan Institute for Stem Cell ‎Biology and Technology, ACECR, Tehran, Iran
4 Department of Chemistry, CICECO - Aveiro Institute of Materials, University of Aveiro, ‎Portugal
5 National Cell Bank Department, Pasteur Institute of Iran, Tehran, Iran
*Corresponding Authors: João F. Mano, Email: jmano@ua.pt; Shahin Bonakdar, Email: shahinbonakdar@yahoo.com


Cell culture-based technologies are widely utilized in various domains such as drug evaluation, toxicity assessment, vaccine and biopharmaceutical development, reproductive technology, and regenerative medicine. It has been demonstrated that pre-adsorption of extracellular matrix (ECM) proteins including collagen, laminin and fibronectin provide more degrees of support for cell adhesion. The purpose of cell imprinting is to imitate the natural topography of cell membranes by gels or polymers to create a reliable environment for the regulation of cell function. The results of recent studies show that cell imprinting is a tool to guide the behavior of cultured cells by controlling their adhesive interactions with surfaces. Therefore, in this review we aim to compare different cell cultures with the imprinting method and discuss different cell imprinting applications in regenerative medicine, personalized medicine, disease modeling, and cell therapy.
First Name
Last Name
Email Address
Security code

Abstract View: 95

Your browser does not support the canvas element.

PDF Download: 388

Your browser does not support the canvas element.

Submitted: 10 Jun 2023
Revision: 13 Sep 2023
Accepted: 19 Sep 2023
ePublished: 28 Nov 2023
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)