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Bioimpacts. 2023;13(2): 85-88.
doi: 10.34172/bi.2023.22023
PMID: 37193078
PMCID: PMC10182445
Scopus ID: 85152106674
  Abstract View: 438
  PDF Download: 368
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Editorial

Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers

Ali Pourali 1, Yadollah Omidi 2* ORCID logo

1 Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran
2 Department of Pharmaceutical Sciences, College of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL33328, USA
*Corresponding Author: Corresponding author: Yadollah Omidi, , Email: yadollah.omidi@gmail.com

Abstract

The molecular marker, cardiac troponin (cTn) is a complex protein that is attached to tropomyosin on the actin filament. It is an essential biomolecule in terms of the calcium-mediated regulation of the contractile apparatus in myofibrils, the release of which is an indication of the dysfunction of cardiomyocytes and hence the initiation of ischemic phenomena in the heart tissue. Fast and accurate analysis of cTn may help the diagnosis and management of acute myocardial infarction (AMI), for which electrochemical biosensors and microfluidics devices can be of great benefit. This editorial aims to highlight the importance of cTn as vital biomarkers in AMI diagnosis.
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Submitted: 01 Feb 2020
Revision: 30 Nov 2021
Accepted: 30 Nov 2021
ePublished: 16 Jan 2022
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