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Editorial
Ali Pourali, Yadollah Omidi* ORCID
Bioimpacts. 2023;13(2): 85-88. doi: 10.34172/bi.2023.22023
PMCID: PMC10182445     PMID: 37193078     Scopus ID: 85152106674    
Professor Yadollah Omidi has a Ph.D. degree in Pharmaceutical Sciences (2003, Cardiff University, UK) and completed a postdoctoral program (2004) at Cardiff University. He is currently working as a full professor at Nova Southeastern University College of Pharmacy, Florida. Prof. Omidi’s research in advanced targeted diagnosis and therapy of diseases have resulted in over 300 published papers in international journals, 27 book chapters, and a few patents.
Original Article
Xiuying Li* ORCID, Xianqin Luo, Shunqin Hu
Bioimpacts. 2023;13(2): 89-96. doi: 10.34172/bi.2023.24166
PMCID: PMC10182444     PMID: 37193073     Scopus ID: 85152093865    
Our results indicated that losartan can modulate the tumor microenvironment, and improve the efficacy of anti-PD-L1 mAb.
Original Article
Raheleh Rafaiee ORCID, Naghmeh Ahmadiankia ORCID, Seyed Abbas Mousavi ORCID, Behnaz Jafari ORCID, Hamid Kalalian Moghaddam* ORCID
Bioimpacts. 2023;13(2): 97-108. doi: 10.34172/bi.2022.23329
PMCID: PMC10182440     PMID: 37193077     Scopus ID: 85152114022    
BMMSCs were significantly higher in IV-treated group compared to the IN route. Moreover, the expression of BDNF and GDNF was higher in IN-treated rats compared with IV treated group.
Original Article
Samira Gholizadeh ORCID, Hossein Haghaei, Hosna Karami, Somaieh Soltani* ORCID, Mostafa Zakariazadeh, Javad Shokri
Bioimpacts. 2023;13(2): 109-121. doi: 10.34172/bi.2022.23383
PMCID: PMC10182447     PMID: 37193080     Scopus ID: 85152094869    
Interaction of the Fingolimod with HSA was studied using multi-spectroscopic and molecular modeling methods. Fingolimod binds to the binding site II of HSA via hydrogen bonds and Van der Walls forces. The binding is enthalpy driven. Fingolimod interaction with HSA leads to the conformational change of HSA.
Original Article
Ali KarbalaeiMahdi ORCID, Kaykhosro Moridi ORCID, Marzieh Ghollasi* ORCID
Bioimpacts. 2023;13(2): 123-132. doi: 10.34172/bi.2022.23713
PMCID: PMC10182442     PMID: 37193074     Scopus ID: 85152111515    
PCL-PANI-GEL fibers showed to be capable candidates for cell attachment and growth. Furthermore, they proved to be of excellent use in bone tissue differentiation.
Original Article
Tina Sepasi ORCID, Farhad Bani, Reza Rahbarghazi, Abbas Ebrahimi-Kalan, Mohammad-Reza Sadeghi, Seyedeh Zahra Alamolhoda, Amir Zarebkohan* ORCID, Tahereh Ghadiri, Huile Gao
Bioimpacts. 2023;13(2): 133-144. doi: 10.34172/bi.2022.23876
PMCID: PMC10182443     PMID: 37193076     Scopus ID: 85152096867    
Efficient gene delivery to the brain using CDX-modified chitosan nanoparticles. Given the vital effects ofcargo's physicochemical features on the targeting ability of functionalized nanoparticles, we successfullyevaluated the brain accumulation of the mentioned nanocomplexes and their distribution in the brain ofmice
Original Article
Raghdah S. Bawadud ORCID, Mayson H. Alkhatib* ORCID
Bioimpacts. 2023;13(2): 145-157. doi: 10.34172/bi.2023.23515
PMCID: PMC10182446     PMID: 37193079     Scopus ID: 85152114664    
Co-delivery of NE-DTX+TQ may probably inhibit the proliferation of T47D via the induction of apoptosis and autophagy pathways and impede the migration by reducing the BCSC population and downregulating TWIST-1 expression to decrease the epithelial-to-mesenchymal transition (EMT) of breast cancer cells
Review
Maryam Sayahinouri ORCID, Sahar Mashayekhi Firouz ORCID, Amin Ebrahimi Sadrabadi ORCID, Mina Masoudnia ORCID, Mahnaz Abdolahi ORCID, Fatemeh Jafarzadeh ORCID, Meshkat Nouripour ORCID, Sana Mirzazadeh ORCID, Nazanin Zangeneh ORCID, Arsalan Jalili* ORCID, Nasser Aghdami ORCID
Bioimpacts. 2023;13(2): 159-179. doi: 10.34172/bi.2023.23839
PMCID: PMC10182441     PMID: 37193075     Scopus ID: 85152105286    
In COVID-19 infection, the various functions of immune cells lead to defense or failure against the virus. Cell therapy is of great importance as a new treatment for COVID-19 infection. Therefore, in this review, we have dealt with the function of immune cells against the SARS-Cov-2 virus and new treatment methods for this disease with the help of different cell types