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BioImpacts. 2022;12: 291-292.
doi: 10.34172/bi.2022.23266
  Abstract View: 94
  PDF Download: 57

Perspective

SARS-CoV-2 and probable lung cancer risk

Sajad Khiali 1 ORCID logo, Afra Rezagholizadeh 1 ORCID logo, Taher Entezari-Maleki 1,2* ORCID logo

1 Department of Clinical Pharmacy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
2 Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
*Corresponding Author: Corresponding author: Taher Entezari-Maleki,, Email: tentezari@gmail.com

Abstract

The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global crisis with a growing number of mortalities and morbidities worldwide. Despite performing numerous researches, there are still considerable unrevealed details regarding the long-term complications and post-infection immunity of the coronavirus disease 2019 (COVID-19). Based on pathophysiological features, SARS-CoV-2 may act similarly as an oncovirus in the lung. This letter summarized three possible oncogenic mechanisms of SARS-CoV-2 that may be associated with lung cancer development.
Keywords: COVID-19, SARS-CoV-2, Oncovirus, Lung cancer, Lung fibrosis
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Submitted: 25 Jul 2020
Revision: 14 Oct 2020
Accepted: 02 Nov 2020
ePublished: 26 Mar 2022
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