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Editorial
Samaneh Alaei ORCID, Hossein Omidian* ORCID
BioImpacts. 2022;12(3): 179-181. doi: 10.34172/bi.2022.24093
PMCID: PMC9124880     PMID: 35677662     Scopus ID: 85132167808    
Hossein Omidian is a professor of pharmaceutical sciences at Nova Southeastern University (NSU). His specific research interests are abuse deterrent formulations to combat opioid abuse, gastro-retentive oral delivery to enhance bioavailability of drugs with narrow absorption window, oral-retentive drug carriers to enhance drug bioavailability in oral cavity, and reduce alcohol absorption into the systemic circulation to combat alcohol overdose and toxicity.
Original Research
Solmaz Zakhireh ORCID, Jaleh Barar* ORCID, Younes Beygi-Khosrowshahi, Abolfazl Barzegari, Yadollah Omidi, Khosro Adibkia* ORCID
BioImpacts. 2022;12(3): 183-193. doi: 10.34172/bi.2021.24
PMCID: PMC9124872     PMID: 35677670     Scopus ID: 85132071807    
The pollen grain of Pistacia vera L. is proposed as a scaffolding building block with the encapsulation capability of bioactive compounds. A modified simple method was developed to create nonallergic hollow pollen grains (HPGs).
Original Research
Ysrafil Ysrafil* ORCID, Indwiani Astuti ORCID
BioImpacts. 2022;12(3): 195-202. doi: 10.34172/bi.2021.22119
PMCID: PMC9124874     PMID: 35677668     Scopus ID: 85132077892    
Chitosan nanoparticle antimiRNA-324-5p could inhibit ovarian cancer proliferation by reduce endogenous miRNA-324-5p to lead restoration of MEN1 and generates repression of GLI1 expression.
Original Research
Shirin Movaghar Asareh ORCID, Tahereh Savei ORCID, Sareh Arjmand* ORCID, Seyed Omid Ranaei Siadat* ORCID, Fataneh Fatemi, Mehrab Pourmadadi, Javad Shabani Shayeh
BioImpacts. 2022;12(3): 203-210. doi: 10.34172/bi.2021.23219
PMCID: PMC9124873     PMID: 35677669     Scopus ID: 85132073917    
Recombinant heavy and light chains of anti-VEGF-A monoclonal Ab Fab fragment were produced in Pichia pastoris. Reconstruction of Fab fragments was verified by anti-Fab Ab and a split system. An electrochemical setup was used to test the interaction of the reconstructed Fab fragment with VEGF-A.
Original Research
Qiang Yang ORCID, Lei Li ORCID, Zhaohui Liu* ORCID, Chunlei Li ORCID, Lili Yu ORCID, Yulin Chang ORCID
BioImpacts. 2022;12(3): 211-218. doi: 10.34172/bi.2021.23401
PMCID: PMC9124878     PMID: 35677666     Scopus ID: 85132068356    
The protective effects of PHC were absent in Nrf2-/- mice. PHC ameliorated RIR-induced lung injury by activating Nrf2 pathway.
Original Research
Forough Shams ORCID, Hamideh Moravvej ORCID, Simzar Hosseinzadeh, Bahram Kazemi, Masoumrh Rajabibazl, Azam Rahimpour* ORCID
BioImpacts. 2022;12(3): 219-231. doi: 10.34172/bi.2021.43
PMCID: PMC9124881     PMID: 35677672     Scopus ID: 85132074833    
The present results highlight the potential of reporter gene targeting for the in vitro analysis of biological processes such as migration.
Original Research
Azam Bozorgi ORCID, Masoud Mozafari ORCID, Mozafar Khazaei ORCID, Mansooreh Soleimani* ORCID, Zahra Jamalpoor* ORCID
BioImpacts. 2022;12(3): 233-246. doi: 10.34172/bi.2021.23451
PMCID: PMC9124876     PMID: 35677664     Scopus ID: 85128388055    
An overview of the fabrication process of pure and Copper (Cu)-substitutednano-hydroxyapatite/chitosan/gelatin (nHA/Cs/Gel) scaffolds followed by the characterization of physical, chemical, and biological properties as proper candidates to bone tissue engineering scaffolds.
Original Research
Marjan Bahraminasab* ORCID, Samaneh Arab, Somaye Ghaffari
BioImpacts. 2022;12(3): 247-259. doi: 10.34172/bi.2021.2330
PMCID: PMC9124877     PMID: 35677667     Scopus ID: 85132130879    
Our in-vitro findings demonstrated that the 75Ti, 50Ti, and 25Ti composites havehigh potential to be used as load-bearing orthopedic materials.
Review
Leila Rostamizadeh ORCID, Ommoleila Molavi* ORCID, Mohsen Rashid, Fatemeh Ramazani, Behzad Baradaran, Afsaneh Lavasanaifar, Raymond Lai
BioImpacts. 2022;12(3): 261-290. doi: 10.34172/bi.2022.23896
PMCID: PMC9124882     PMID: 35677663     Scopus ID: 85132074584    
In this paper, we will review the application of the four most widely studied TLR agonists including agonists of TLR3, 4, 7, and 9 in cancer immunotherapy.
Perspective
Sajad Khiali ORCID, Afra Rezagholizadeh ORCID, Taher Entezari-Maleki* ORCID
BioImpacts. 2022;12(3): 291-292. doi: 10.34172/bi.2022.23266
PMCID: PMC9124879     PMID: 35677665     Scopus ID: 85132071249    
In the present perspective piece, three possible mechanisms of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as an oncogenic virus in the lung have been discussed.
Letter to the Editor
Robert C. Speth* ORCID
BioImpacts. 2022;12(3): 293-294. doi: 10.34172/bi.2022.24124
PMCID: PMC9124875     PMID: 35677671     Scopus ID: 85132072457