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BioImpacts. 2022;12(3): 233-246. doi: 10.34172/bi.2021.23451
PMID: 35677664        PMCID: PMC9124876

Original Research

Fabrication, characterization, and optimization of a novel copper-incorporated chitosan/gelatin-based scaffold for bone tissue engineering applications

Azam Bozorgi 1 ORCID, Masoud Mozafari 1 ORCID, Mozafar Khazaei 2 ORCID, Mansooreh Soleimani 3 * ORCID, Zahra Jamalpoor 4 * ORCID

Cited by CrossRef: 2


1- Bozorgi A, Khazaei M, Bozorgi M, Sabouri L, Soleimani M, Jamalpoor Z. Bifunctional tissue‐engineered composite construct for bone regeneration: The role of copper and fibrin. J Biomed Mater Res. 2024;112(1) [Crossref]
2- Akbarpour M, Farajnezhad F, Poureshagh A, Moniri Javadhesari S. Effects of Copper Doping on Fluorohydroxyapatite Coating: Analysis of Microstructure, Biocompatibility, Corrosion Resistance, and Cell Adhesion Characteristics. Inorg Chem. 2024;63(43):20314 [Crossref]
3- Kumari S, Singh D, Srivastava P, Singh B, Mishra A. Generation of graphene oxide and nano-bioglass based scaffold for bone tissue regeneration. Biomed Mater. 2022;17(6):065012 [Crossref]
4- Soltani L, Varmira K, Nazari M. Comparison of the differentiation of ovine fetal bone-marrow mesenchymal stem cells towards osteocytes on chitosan/alginate/CuO-NPs and chitosan/alginate/FeO-NPs scaffolds. Sci Rep. 2024;14(1) [Crossref]
5- Dai X, Yuan M, Yang Y, Dang M, Yang J, Shi J, Liu D, Li M, Yao H, Fei W. Dual cross-linked COL1/HAp bionic gradient scaffolds containing human amniotic mesenchymal stem cells promote rotator cuff tendon–bone interface healing. Biomaterials Advances. 2024;158:213799 [Crossref]
6- Souto-Lopes M, Grenho L, Manrique Y, Dias M, Lopes J, Fernandes M, Monteiro F, Salgado C. Bone regeneration driven by a nano-hydroxyapatite/chitosan composite bioaerogel for periodontal regeneration. Front Bioeng Biotechnol. 2024;12 [Crossref]
7- Burdușel A, Gherasim O, Andronescu E, Grumezescu A, Ficai A. Inorganic Nanoparticles in Bone Healing Applications. Pharmaceutics. 2022;14(4):770 [Crossref]
8- Bozorgi A, Khazaei M, Bozorgi M, Jamalpoor Z. Apigenin Release from Chitosan/Gelatin Membranes Promotes Osteogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells. J Med Biol Eng. 2024;44(1):1 [Crossref]
9- Han C, Lu D, Yang S, Liu C, Guo F, Zhang K, Li P. Copper ion-doped multifunctional hydrogel with mild photothermal enhancement promotes vascularized bone regeneration. J Biomater Appl. 2024;39(4):332 [Crossref]


As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge