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Bioimpacts. 2018;8(1): 23-30. doi: 10.15171/bi.2018.04
PMID: 29713599        PMCID: PMC5915705

Original Research

Caralluma umbellata Haw. protects liver against paracetamol toxicity and inhibits CYP2E1

Pavan Kumar Bellamakondi * , Ashok Godavarthi, Mohammed Ibrahim

Cited by CrossRef: 9


1- Jayaprakash K, Manokari M, Cokulraj M, Dey A, Faisal M, Alatar A, Joshee N, Shekhawat M. Improved organogenesis and micro-structural traits in micropropagated plantlets of Caralluma umbellata Haw. in response to Meta-Topolin. Plant Cell Tiss Organ Cult. 2023;153(1):105 [Crossref]
2- Sarkar C, Mondal M, Al-Khafaji K, El-Kersh D, Jamaddar S, Ray P, Roy U, Afroze M, Moniruzzaman M, Khan M, Asha U, Khalipha A, Mori E, de Lacerda B, Araújo I, Coutinho H, Shill M, Islam M. GC–MS analysis, and evaluation of protective effect of Piper chaba stem bark against paracetamol-induced liver damage in Sprague-Dawley rats: Possible defensive mechanism by targeting CYP2E1 enzyme through in silico study. Life Sciences. 2022;309:121044 [Crossref]
3- Zhao S, Zhang J, Sun X, Yangzom C, Shang P. Mitochondrial calcium uniporter involved in foodborne mycotoxin-induced hepatotoxicity. Ecotoxicology and Environmental Safety. 2022;237:113535 [Crossref]
4- Rao Rao Shimoga Janakirama A, Mathad Shivayogi S, Kolkar Satyanarayana J, Chapeyil Kumaran R. Characterization of isolated compounds from Morus spp. and their biological activity as anticancer molecules. Bioimpacts. 2020;11(3):187 [Crossref]
5- Eraky S, Abo El-Magd N. Omega-3 fatty acids protect against acetaminophen-induced hepatic and renal toxicity in rats through HO-1-Nrf2-BACH1 pathway. Archives of Biochemistry and Biophysics. 2020;687:108387 [Crossref]
6- Alipour M, Karimi-Sales E. Molecular mechanisms of protective roles of isoflavones against chemicals-induced liver injuries. Chemico-Biological Interactions. 2020;329:109213 [Crossref]
7- Vignesh A, Amal T, Janani Sree S, Selvakumar S, Vasanth K. Conservation linkages of endangered medicinal plant and exploration of phytochemicals, pharmaceutical screening and in silico validation against diabetics using in vivo wild and in vitro regenerated plant Boucerosia diffusa Wight.. 3 Biotech. 2023;13(7) [Crossref]
8- Abo El-Magd N, Eraky S. The molecular mechanism underlining the preventive effect of vitamin D against hepatic and renal acute toxicity through the NrF2/ BACH1/ HO-1 pathway. Life Sciences. 2020;244:117331 [Crossref]
9- Ren Y, Xu Z, Qiao Z, Wang X, Yang C. Flaxseed Lignan Alleviates the Paracetamol-Induced Hepatotoxicity Associated with Regulation of Gut Microbiota and Serum Metabolome. Nutrients. 2024;16(2):295 [Crossref]


As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge