Logo-bi
Bioimpacts. 2016;6(1): 3-8. doi: 10.15171/bi.2016.01
PMID: 27340618        PMCID: PMC4916549

Original Research

Sulfasalazine-induced renal and hepatic injury in rats and the protective role of taurine

Reza Heidari 1, Maryam Rasti 2, Babak Shirazi Yeganeh 3, Hossein Niknahad 1,2 * , Arastoo Saeedi 2, Asma Najibi 1,2

Cited by CrossRef: 38

1- Refaat B, El-Boshy M. Protective antioxidative and anti-inflammatory actions of β-caryophyllene against sulfasalazine-induced nephrotoxicity in rat. Exp Biol Med (Maywood). 2022;247(8):691 [Crossref]
2- Heidari R, Niknahad H, Sadeghi A, Mohammadi H, Ghanbarinejad V, Ommati M, Hosseini A, Azarpira N, Khodaei F, Farshad O, Rashidi E, Siavashpour A, Najibi A, Ahmadi A, Jamshidzadeh A. Betaine treatment protects liver through regulating mitochondrial function and counteracting oxidative stress in acute and chronic animal models of hepatic injury. Biomedicine & Pharmacotherapy. 2018;103:75 [Crossref]
3- Surai P, Earle-Payne K, Kidd M. Taurine as a Natural Antioxidant: From Direct Antioxidant Effects to Protective Action in Various Toxicological Models. Antioxidants. 2021;10(12):1876 [Crossref]
4- Farshad O, Heidari R, Zamiri M, Retana-Márquez S, Khalili M, Ebrahimi M, Jamshidzadeh A, Ommati M. Spermatotoxic Effects of Single-Walled and Multi-Walled Carbon Nanotubes on Male Mice. Front Vet Sci. 2020;7 [Crossref]
5- Catanzaro R, Marotta F, Yazdani A, Sciuto M. Inflammatory Bowel Disease Therapies and Acute Liver Injury. Toxics. 2024;12(6):421 [Crossref]
6- Liu Y, Wu J, Chen L, Wu X, Gan Y, Xu N, Li M, Luo H, Guan F, Su Z, Chen J, Li Y. β-patchoulene simultaneously ameliorated dextran sulfate sodium-induced colitis and secondary liver injury in mice via suppressing colonic leakage and flora imbalance. Biochemical Pharmacology. 2020;182:114260 [Crossref]
7- Vasudevan S, Samuels I, Park P. Gpr75 knockout mice display age‐dependent cone photoreceptor cell loss. Journal of Neurochemistry. 2023;167(4):538 [Crossref]
8- Mani R, Natesan V, Arumugam R. Neuroprotective effect of chrysin on hyperammonemia mediated neuroinflammatory responses and altered expression of astrocytic protein in the hippocampus. Biomedicine & Pharmacotherapy. 2017;88:762 [Crossref]
9- Hamilton L, Collins-Yoder A, Collins R. Drug-Induced Liver Injury. 2016;27(4):430 [Crossref]
10- Heidari R. The footprints of mitochondrial impairment and cellular energy crisis in the pathogenesis of xenobiotics-induced nephrotoxicity, serum electrolytes imbalance, and Fanconi’s syndrome: A comprehensive review. Toxicology. 2019;423:1 [Crossref]
11- Ommati M, Sabouri S, Niknahad H, Arjmand A, Alidaee S, Mazloomi S, Najibi A, Rezaei H, Ghiasvand A, Ahmadi P, Nikoozadeh A, Khodaei F, Abdoli N, Azarpira N, Heidari R. Pulmonary inflammation, oxidative stress, and fibrosis in a mouse model of cholestasis: the potential protective properties of the dipeptide carnosine. Naunyn-Schmiedeberg's Arch Pharmacol. 2023;396(6):1129 [Crossref]
12- Emadi E, Abdoli N, Ghanbarinejad V, Mohammadi H, Mousavi Mobarakeh K, Azarpira N, Mahboubi Z, Niknahad H, Heidari R. The potential role of mitochondrial impairment in the pathogenesis of imatinib-induced renal injury. Heliyon. 2019;5(6):e01996 [Crossref]
13- Niknahad H, Mobasheri A, Arjmand A, Rafiei E, Alidaee S, Razavi H, Bagheri S, Rezaei H, Sabouri S, Najibi A, Khodaei F, Kashani S, Ommati M, Heidari R. Hepatic encephalopathy complications are diminished by piracetam via the interaction between mitochondrial function, oxidative stress, inflammatory response, and locomotor activity. Heliyon. 2023;9(10):e20557 [Crossref]
14- Farshad O, Ommati M, Yüzügülen J, Jamshidzadeh A, Mousavi K, Ahmadi Z, Azarpira N, Ghaffari H, Najibi A, Shafaghat M, Niknahad H, Heidari R. Carnosine Mitigates Biomarkers of Oxidative Stress, Improves Mitochondrial Function, and Alleviates Histopathological Alterations in the Renal Tissue of Cholestatic Rats . Pharm Sci. 2020;27(1):32 [Crossref]
15- Cao Y, Huang Z, You S, Guo W, Zhang F, Liu B, Lv X, Lin Z, Liu P. The Protective Effects of Ganoderic Acids from Ganoderma lucidum Fruiting Body on Alcoholic Liver Injury and Intestinal Microflora Disturbance in Mice with Excessive Alcohol Intake. Foods. 2022;11(7):949 [Crossref]
16- Abdoli N, Sadeghian I, Mousavi K, Azarpira N, Ommati M, Heidari R. Suppression of cirrhosis-related renal injury by N-acetyl cysteine. Current Research in Pharmacology and Drug Discovery. 2020;1:30 [Crossref]
17- Qiao Y, He H, Zhang Z, Liao Z, Yin D, Liu D, Yi B, He M. Long-Term Sodium Ferulate Supplementation Scavenges Oxygen Radicals and Reverses Liver Damage Induced by Iron Overloading. Molecules. 2016;21(9):1219 [Crossref]
18- Ye W, Ding Y, Li M, Tian Z, Wang S, Liu Z. Safety assessment of sulfasalazine: a pharmacovigilance study based on FAERS database. Front Pharmacol. 2024;15 [Crossref]
19- Li Y, Shen J, Lu S, Zhu L, Wang B, Bai M, Xu E. Transcriptomic analysis reveals the mechanism of sulfasalazine-induced liver injury in mice. Toxicology Letters. 2020;321:12 [Crossref]
20- Keshavarzi M, Naraki K, Razavi B, Hosseinzadeh H. A narrative review and new insights into the protective effects of taurine against drug side effects. Naunyn-Schmiedeberg's Arch Pharmacol. 2024; [Crossref]
21- Ommati M, Mobasheri A, Ma Y, Xu D, Tang Z, Manthari R, Abdoli N, Azarpira N, Lu Y, Sadeghian I, Mousavifaraz A, Nadgaran A, Nikoozadeh A, Mazloomi S, Mehrabani P, Rezaei M, Xin H, Mingyu Y, Niknahad H, Heidari R. Taurine mitigates the development of pulmonary inflammation, oxidative stress, and histopathological alterations in a rat model of bile duct ligation. Naunyn-Schmiedeberg's Arch Pharmacol. 2022;395(12):1557 [Crossref]
22- Ommati M, Nozhat Z, Sabouri S, Kong X, Retana-Márquez S, Eftekhari A, Ma Y, Evazzadeh F, Juárez-Rojas L, Heidari R, Wang H. Pesticide-Induced Alterations in Locomotor Activity, Anxiety, and Depression-like Behavior Are Mediated through Oxidative Stress-Related Autophagy: A Persistent Developmental Study in Mice. J Agric Food Chem. 2024;72(19):11205 [Crossref]
23- Doba S, Buzlama A. Protective effect of three developed gel formulations: Chitosan, Chitosan with Taurine and Chitosan with Dexpanthenol, on the acute overdose of Diclofenac sodium in preclinical studies. RJPT. 2021;:4341 [Crossref]
24- Zhao H, Yang G, Sun N, Kong Y, Liu Y. Efficacy and safety of stellate ganglion block in chronic ulcerative colitis. WJG. 2017;23(3):533 [Crossref]
25- Darabi F, Keshavarzi M, Abdullah M, Dehghani F, Khanjani N, yousefinejad S, Khajehnasiri F, Zamanian Z. Evaluation of oxidative stress and biochemical biomarkers, and psychological parameters in cement plant workers. Toxicol Ind Health. 2022;38(1):29 [Crossref]
26- Ommati M, Sabouri S, Retana-Marquez S, Nategh Ahmadi H, Arjmand A, Alidaee S, Mazloomi S, Akhlagh A, Abdoli N, Niknahad H, Jamshidzadeh A, Ma Y, Azarpira N, Asefi Y, Heidari R. Taurine Improves Sperm Mitochondrial Indices, Blunts Oxidative Stress Parameters, and Enhances Steroidogenesis and Kinematics of Sperm in Lead-Exposed Mice. Reprod Sci. 2023;30(6):1891 [Crossref]
27- Ommati M, Farshad O, Jamshidzadeh A, Heidari R. Taurine enhances skeletal muscle mitochondrial function in a rat model of resistance training. PharmaNutrition. 2019;9:100161 [Crossref]
28- Kim Y, Song J, Kim Y, Lee K, Lee S, Kim N. Effect of the stellate ganglion block on symptoms of ulcerative colitis. 2021;100(29):e26684 [Crossref]
29- Ommati M, Heidari R, Jamshidzadeh A, Zamiri M, Sun Z, Sabouri S, Wang J, Ahmadi F, Javanmard N, Seifi K, Mousapour S, Yeganeh B. Dual effects of sulfasalazine on rat sperm characteristics, spermatogenesis, and steroidogenesis in two experimental models. Toxicology Letters. 2018;284:46 [Crossref]
30- Ommati M, Rezaei H, Socorro R, Tian W, Zhao J, Rouhani A, Sabouri S, Ghaderi F, Niknahad A, Najibi A, Mazloomi S, Safipour M, Honarpishefard Z, Wang H, Niknahad H, Heidari R. Pre/postnatal taurine supplementation improves neurodevelopment and brain function in mice offspring: A persistent developmental study from puberty to maturity. Life Sciences. 2024;336:122284 [Crossref]
31- Mousavi K, Manthari R, Najibi A, Jia Z, Ommati M, Heidari R. Mitochondrial dysfunction and oxidative stress are involved in the mechanism of tramadol-induced renal injury. Current Research in Pharmacology and Drug Discovery. 2021;2:100049 [Crossref]
32- Xia P, Hou T, Ma M, Li S, Jin H, Luo X, Li J, Geng F, Li B. Konjac oligosaccharides attenuate DSS-induced ulcerative colitis in mice: mechanistic insights. Food Funct. 2022;13(10):5626 [Crossref]

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge