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Bioimpacts. 2016;6(1): 33-39. doi: 10.15171/bi.2016.05
PMID: 27340622        PMCID: PMC4916550

Original Research

Protective mechanisms of Cucumis sativus in diabetes-related models of oxidative stress and carbonyl stress

Himan Heidari 1,2, Mohammad Kamalinejad 3, Maryam Noubarani 2, Mokhtar Rahmati 2, Iman Jafarian 2, Hasan Adiban 2, Mohammad Reza Eskandari 1,2 *

Cited by CrossRef: 17


1- Andalib S, Maleki Nejad N, Kamali Nejad M, Tavakolizadeh M, Noubarani M, Shahbazi Zanjanmaskan S, Eskandari M. A search for protective activity of aqueous extract of Punica granatum var. pleniflora against CCl4-induced hepatotoxicity in rats. J Med Plants. 2020;19(75):188 [Crossref]
2- Huang Y, Li X, Zhang X, Tang J, Rana M. Oxymatrine Ameliorates Memory Impairment in Diabetic Rats by Regulating Oxidative Stress and Apoptosis: Involvement of NOX2/NOX4. Oxidative Medicine and Cellular Longevity. 2020;2020:1 [Crossref]
3- Adomako-Bonsu A, Jacobsen J, Maser E. Metabolic activation of 2,4,6-trinitrotoluene; a case for ROS-induced cell damage. Redox Biology. 2024;72:103082 [Crossref]
4- Lotfi M, Behpoor N, Rahimi M, Jafari A. Separate and Combined Effects of Resistance Training and Cucumber (Cucumis sativus) Juice Consumption on the Diabetic Indicators and Lipid Profile in Women with Type 2 Diabetes. J Kermanshah Univ Med Sci. 2023;27(2) [Crossref]
5- Pignotti G, Hook G, Ghan E, Vega-López S. Effect of nopales ( Opuntia spp.) on lipoprotein profile and oxidative stress among moderately hypercholesterolemic adults: A pilot study. Journal of Functional Foods. 2016;27:115 [Crossref]
6- Sattar S, Ali F, Iftikhar M, Saleem A, Maha M, Wajid M, Nisar M. Biological Components in Cucumbers (Cucumis Sativus L.): Implications for Pickle Manufacturing and Health Benefits in Fresh and Processed Varieties. Qeios. 2024; [Crossref]
7- Li Y, Li Y, Fang Z, Huang D, Yang Y, Zhao D, Hang M, Wang J. The effect of Malus doumeri leaf flavonoids on oxidative stress injury induced by hydrogen peroxide (H2O2) in human embryonic kidney 293 T cells. BMC Complement Med Ther. 2020;20(1) [Crossref]
8- Trejo-Moreno C, Méndez-Martínez M, Zamilpa A, Jiménez-Ferrer E, Perez-Garcia M, Medina-Campos O, Pedraza-Chaverri J, Santana M, Esquivel-Guadarrama F, Castillo A, Cervantes-Torres J, Fragoso G, Rosas-Salgado G. Cucumis sativus Aqueous Fraction Inhibits Angiotensin II-Induced Inflammation and Oxidative Stress In Vitro. Nutrients. 2018;10(3):276 [Crossref]
9- Tang J, Yang X, Zhao F, Zhang D, Mo S, Ye Y. Visualizing peroxynitrite fluxes and protective effect of endogenous hydrogen sulfide during carbonyl stress in endothelial cell. Sensors and Actuators B: Chemical. 2021;330:129283 [Crossref]
10- Tan B, Norhaizan M, Liew W, Sulaiman Rahman H. Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases. Front Pharmacol. 2018;9 [Crossref]
11- Mokhtari E, Farhadnejad H, Salehi-Sahlabadi A, Najibi N, Azadi M, Teymoori F, Mirmiran P. Spinach consumption and nonalcoholic fatty liver disease among adults: a case–control study. BMC Gastroenterol. 2021;21(1) [Crossref]
12- Thanthong S, Nanthong R, Kongwattanakul S, Laebua K, Trirussapanich P, Pitiporn S, Nantajit D. Prophylaxis of Radiation-Induced Dermatitis in Patients With Breast Cancer Using Herbal Creams: A Prospective Randomized Controlled Trial. Integr Cancer Ther. 2020;19 [Crossref]
13- Pérez-Piñero S, Muñoz-Carrillo J, Victoria-Montesinos D, García-Muñoz A, Ávila-Gandía V, López-Román F. Effectiveness of a Cucumber Extract Supplement on Articular Pain in Patients with Knee Osteoarthritis: A Randomized Double-Blind Controlled Clinical Trial. Applied Sciences. 2022;13(1):485 [Crossref]


As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge