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Bioimpacts. 2017;7(1): 5-12. doi: 10.15171/bi.2017.02
PMID: 28546948        PMCID: PMC5439390

Original Research

Liquigroud technique: a new concept for enhancing dissolution rate of glibenclamide by combination of liquisolid and co-grinding technologies

Leila Azharshekoufeh 1, Javad Shokri 1, Mohammad Barzegar-Jalali 1,2, Yousef Javadzadeh 1,3 *

Cited by CrossRef: 12

1- Thakkar H, Vasava D, Patel A, Dhande R. Formulation and Evaluation of Liquisolid Compacts of Itraconazole to Enhance Its Oral Bioavailability. Ther Deliv. 2020;11(2):83 [Crossref]
2- Mukherjee S, Maity S, Ghosh B, Chakraborty T, Mondal A, Bishayee A. Assessment of the antidiabetic potentiality of glyburide loaded glyceryl monostearate solid lipid nanoparticles. Journal of Drug Delivery Science and Technology. 2020;55:101451 [Crossref]
3- Sabbaghi N, Dadfarnia S, Haji Shabani A, Farsadrooh M. Dispersive micro solid phase extraction of glibenclamide from plasma, urine, and wastewater using a magnetic molecularly imprinted polymer followed by its determination by a high-performance liquid chromatography-photodiode array detector. RSC Adv. 2024;14(19):13168 [Crossref]
4- Bonthagarala B, Dasari V, Kotra V. Solubility Enhancement Effect at Absorption Site on Bioavailability of Ritonavir Using Liquisolid Technique. Ther Deliv. 2019;10(5):295 [Crossref]
5- Nazem N, Shokri J, Nourani N, Zangi A, Lam M, Nokhodchi A, Javadzadeh Y. Combining Liquisolid and Co-grinding Techniques to Enhance the Dissolution Rate of Celecoxib. J Pharm Innov. 2023;18(1):300 [Crossref]
6- Molaei M, Osouli-Bostanabad K, Adibkia K, Shokri J, Asnaashari S, Javadzadeh Y. Enhancement of ketoconazole dissolution rate by the liquisolid technique. 2018;68(3):325 [Crossref]
7- Srivastava D, Fatima Z, Kaur C, Mishra A, Nashik S, Rizvi D, Prasad R. Glibenclamide–malonic acid cocrystal with an enhanced solubility and bioavailability. Drug Development and Industrial Pharmacy. 2022;48(8):417 [Crossref]
8- Akhtar F, Akhtar S, Ashfaq S, Rehman I, Mirza A. UV Spectroscopic Method for Optimization and Determination of Glibenclamide in Bulk, Pharmaceutical Dosage Form and its Application for In Vitro Interaction Studies. J Anal Test. 2020;4(4):281 [Crossref]
9- Effiong D, Onunkwo G. Principles, Applications and Limitations of the Liquisolid System of Drug Delivery: A Review. Trends Med Res. 2024;19(1):178 [Crossref]
10- Sharma S, Arora V, Sharma T. An Effective Approach to Enhance the Dissolution Profile of Curcumin and Quercetin: Liquisolid Compacts. LDDD. 2024;21(7):1172 [Crossref]
11- Jaipakdee N, Tabboon P, Ekkanjanakorn P, Sonchiangkham K, Pongjanyakul T, Limpongsa E. Physicochemical and Release Characteristics of Andrographolide Liquisolid Systems Fabricated Based on Microcrystalline Cellulose, Magnesium Aluminometasilicate, and Their Blends. Polymers. 2026;18(21):2667 [Crossref]
12- Gupta K, Dakhole M, Jinnawar K, Umekar M. Strategies for improving hydrophobic drugs solubility and bioavailability. IJPCA. 2023;10(3):164 [Crossref]
13- Rashad A, Louis D. An Overview on Liquisolid Technique: Its Development and Applications. Ther Deliv. 2022;13(12):577 [Crossref]

Poster

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate (2025): 19% 
Publication fee: Free of charge

Indexing/Abstracting Info
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