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Bioimpacts. 2014;4(4): 191-198. doi: 10.15171/bi.2014.019
PMID: 25671175        PMCID: PMC4298710

Original Research

Geno/cytotoxicty and Apoptotic Properties of Phenolic Compounds from the Seeds of Dorema Glabrum Fisch. C.A

Morteza Eskandani 1,2, Elmira Dadizadeh 3, Hamed Hamishehkar 4, Hossein Nazemiyeh 1,3 * , Jaleh Barar 1,3 * ORCID

Cited by CrossRef: 18


1- Naeem F, Khan S, Jalil A, Ranjha N, Riaz A, Haider M, Sarwar S, Saher F, Afzal S. pH responsive cross-linked polymeric matrices based on natural polymers: effect of process variables on swelling characterization and drug delivery properties. Bioimpacts. 2017;7(3):177 [Crossref]
2- Jafari S, Maleki-Dizaji N, Barar J, Barzegar-Jalali M, Rameshrad M, Adibkia K. Methylprednisolone acetate-loaded hydroxyapatite nanoparticles as a potential drug delivery system for treatment of rheumatoid arthritis: In vitro and in vivo evaluations. European Journal of Pharmaceutical Sciences. 2016;91:225 [Crossref]
3- Nakhlband A, Eskandani M, Saeedi N, Ghafari S, Omidi Y, Barar J, Garjani A. Marrubiin-loaded solid lipid nanoparticles’ impact on TNF-α treated umbilical vein endothelial cells: A study for cardioprotective effect. Colloids and Surfaces B: Biointerfaces. 2018;164:299 [Crossref]
4- Bahadori M, Eskandani M, De Mieri M, Hamburger M, Nazemiyeh H. Anti-proliferative activity-guided isolation of clerodermic acid from Salvia nemorosa L.: Geno/cytotoxicity and hypoxia-mediated mechanism of action. Food and Chemical Toxicology. 2018;120:155 [Crossref]
5- Kafil V, Eskandani M, Omidi Y, Nazemiyeh H, Barar J. Abietane diterpenoid of Salvia sahendica Boiss and Buhse potently inhibits MCF-7 breast carcinoma cells by suppression of the PI3K/AKT pathway. RSC Adv. 2015;5(23):18041 [Crossref]
6- Rabizadeh F, Naseri S. Environmental parameters and habitats of Dorema ammoniacum (D. Don) in south-central Alborz Dorema ammoniacum (D. Don) habitat parameters in south-central Alborz. Int J Environ Sci Technol. 2023;20(1):725 [Crossref]
7- Rahmanian N, Shokrzadeh M, Eskandani M. Recent advances in γH2AX biomarker-based genotoxicity assays: A marker of DNA damage and repair. DNA Repair. 2021;108:103243 [Crossref]
8- Salmanzadeh R, Eskandani M, Mokhtarzadeh A, Vandghanooni S, Ilghami R, Maleki H, Saeeidi N, Omidi Y. Propyl gallate (PG) and tert-butylhydroquinone (TBHQ) may alter the potential anti-cancer behavior of probiotics. Food Bioscience. 2018;24:37 [Crossref]
9- Kantawong F, Singhatong S, Aomjai A, Boonyuen K, Mooti N, Wanachantararak P, Kuboki T. Properties of macerated herbal oil. Bioimpacts. 2017;7(1):13 [Crossref]
10- Vandghanooni S, Farajzadeh Vahid Z, Nakhlband A, Bahadori M, Eskandani M. Sclareol Inhibits Hypoxia-Inducible Factor-1α Accumulation and Induces Apoptosis in Hypoxic Cancer Cells. Adv Pharm Bull. 2022;12(3):593 [Crossref]
11- Das G, Das S, Talukdar A, Venil C, Bose S, Banerjee S, Shin H, Gutiérrez-Grijalva E, Heredia J, Patra J. Pharmacology and Ethnomedicinal Potential of Selected Plants Species from Apiaceae (Umbelliferae). CCHTS. 2023;26(2):256 [Crossref]
12- Jafari S, Maleki-Dizaji N, Barar J, Barzegar-Jalali M, Rameshrad M, Adibkia K. Physicochemical characterization and in vivo evaluation of triamcinolone acetonide-loaded hydroxyapatite nanocomposites for treatment of rheumatoid arthritis. Colloids and Surfaces B: Biointerfaces. 2016;140:223 [Crossref]
13- Rasouliyan F, Eskandani M, Jaymand M, Akbari Nakhjavani S, Farahzadi R, Vandghanooni S, Eskandani M. Preparation, physicochemical characterization, and anti-proliferative properties of Lawsone-loaded solid lipid nanoparticles. Chemistry and Physics of Lipids. 2021;239:105123 [Crossref]
14- Hamishehkar H, Bahadori M, Vandghanooni S, Eskandani M, Nakhlband A, Eskandani M. Preparation, characterization and anti-proliferative effects of sclareol-loaded solid lipid nanoparticles on A549 human lung epithelial cancer cells. Journal of Drug Delivery Science and Technology. 2018;45:272 [Crossref]
15- Zibaee E, Amiri M, Boghrati Z, Farhadi F, Ramezani M, Emami S, Sahebkar A. Ethnomedicinal Uses, Phytochemistry and Pharmacology ofDoremaSpecies (Apiaceae): A Review. J Pharmacopuncture. 2020;23(3):91 [Crossref]
16- Hossiniyan S, ghalamfarsa F, Rostami yasuj S, salehpour Z, Latifpour M, hassanzadeh S, Mohammadi B, Jadidi-Niaragh F, Ganji A, Ghalamfarsa G. Chemical composition and cytotoxic activity of the essential oil from the aerial parts ofDorema aucheri. J Herbmed Pharmacol. 2021;10(3):344 [Crossref]
17- Lou Y, Wu H, Zheng J, He X, Wu Z, Lu X, Qiu Y. Determination and pharmacokinetic study of skimmin by UHPLC-MS/MS in rat plasma. Journal of Pharmaceutical and Biomedical Analysis. 2020;179:112969 [Crossref]
18- Wang G, Wu Y, Liu J, Li C. Upregulation of miR-98 Inhibits Apoptosis in Cartilage Cells in Osteoarthritis. Genetic Testing and Molecular Biomarkers. 2016;20(11):645 [Crossref]


As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge