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Bioimpacts. 2017;7(3): 155-166. doi: 10.15171/bi.2017.19
PMID: 29159143        PMCID: PMC5684507

Original Research

"Grafting-from" synthesis and characterization of poly (2-ethyl-2-oxazoline)-b-poly (benzyl L-glutamate) micellar nanoparticles for potential biomedical applications

Mohsen Salmanpour 1, Ali Tamaddon 2 * , Gholamhossein Yousefi 1,2, Soliman Mohammadi-Samani 1,2

Cited by CrossRef: 15


1- Engel N, Hoffmann T, Behrendt F, Liebing P, Weber C, Gottschaldt M, Schubert U. Cryogels Based on Poly(2-oxazoline)s through Development of Bi- and Trifunctional Cross-Linkers Incorporating End Groups with Adjustable Stability. Macromolecules. 2024;57(6):2915 [Crossref]
2- Salmanpour M, Yousefi G, Mohammadi-Samani S, Abedanzadeh M, Tamaddon A. Hydrolytic stabilization of irinotecan active metabolite (SN38) against physiologic pH through self-assembly of conjugated poly (2-oxazoline) - poly (l-amino acid) block copolymer: A-synthesis and physicochemical characterization. Journal of Drug Delivery Science and Technology. 2020;60:101933 [Crossref]
3- Abdeen S, Hefni H, Awadallah-F A, El-Rahman N. The synergistic effect of biochar and poly(2-ethyl-2-oxazoline)/poly(2-hydroxyethylmethacarylate)/chitosan) hydrogels on saline soil properties and carrot productivity. Chem Biol Technol Agric. 2023;10(1) [Crossref]
4- El Jundi A, Buwalda S, Bakkour Y, Garric X, Nottelet B. Double hydrophilic block copolymers self-assemblies in biomedical applications. Advances in Colloid and Interface Science. 2020;283:102213 [Crossref]
5- Blum S, Schollmeyer D, Turks M, Waldvogel S. Metal‐ and Reagent‐Free Electrochemical Synthesis of Alkyl Arylsulfonates in a Multi‐Component Reaction. Chemistry A European J. 2020;26(38):8358 [Crossref]
6- Salmanpour M, Saeed-Vaghefi M, Abolmaali S, Tamaddon A. Sterically Stabilized Polyionic Complex Nanogels of Chitosan Lysate and PEG-b-Polyglutamic Acid Copolymer for the Delivery of Irinotecan Active Metabolite (SN-38). CDD. 2021;18(6):741 [Crossref]
7- Abedanzadeh M, Salmanpour M, Farjadian F, Mohammadi S, Tamaddon A. Curcumin loaded polymeric micelles of variable hydrophobic lengths by RAFT polymerization: Preparation and in-vitro characterization. Journal of Drug Delivery Science and Technology. 2020;58:101793 [Crossref]
8- Mostoufi H, Yousefi G, Tamaddon A, Firuzi O. Reversing multi-drug tumor resistance to Paclitaxel by well-defined pH-sensitive amphiphilic polypeptide block copolymers via induction of lysosomal membrane permeabilization. Colloids and Surfaces B: Biointerfaces. 2019;174:17 [Crossref]
9- Heidari M, Salmanpour M, Tamaddon A. Implication of nanotechnology-based approaches to combat SARS-CoV-2 infection. 2021;53(1):78 [Crossref]
10- Deng H, Wang J, He W, Ye Y, Bai R, Zhang X, Ye X, Xie T, Hui Z. Microwave-assisted rapid synthesis of chiral oxazolines. Org Biomol Chem. 2023;21(11):2312 [Crossref]
11- An J, Ma Y, Zhao W, Hu Y, Wang Y, Zhang Z, Luo X, Zhang B, Ding Y, Liu Y. Drug repurposing strategy II: from approved drugs to agri-fungicide leads. J Antibiot. 2023;76(3):131 [Crossref]
12- Ghosh B, Biswas S. Polymeric micelles in cancer therapy: State of the art. Journal of Controlled Release. 2021;332:127 [Crossref]
13- Monajati M, Tavakoli S, yousefi G, Abolmaali S, Tamaddon A. Effect of PEGylation on assembly morphology and cellular uptake of poly ethyleneimine-cholesterol conjugates for delivery of sorafenib tosylate in hepatocellular carcinoma. Bioimpacts. 2018;8(4):241 [Crossref]
14- Salmanpour M, Yousefi G, Samani S, Mohammadi S, Anbardar M, Tamaddon A. Nanoparticulate delivery of irinotecan active metabolite (SN38) in murine colorectal carcinoma through conjugation to poly (2-ethyl 2-oxazoline)-b-poly (L-glutamic acid) double hydrophilic copolymer. European Journal of Pharmaceutical Sciences. 2019;136:104941 [Crossref]
15- Patel H, Li J, Bo L, Mehta R, Ashby C, Wang S, Cai W, Chen Z. Nanotechnology-based delivery systems to overcome drug resistance in cancer. 2024;4(1):5 [Crossref]
16- Alimardani V, Sadat Abolmaali S, Yousefi G, Hossein Nowroozzadeh M, Mohammad Tamaddon A. In-situ nanomicelle forming microneedles of poly NIPAAm-b-poly glutamic acid for trans-scleral delivery of dexamethasone. Journal of Industrial and Engineering Chemistry. 2023;119:485 [Crossref]
17- Su Z, Takeda Y, Matsui D, Toyotake Y, Wakayama M. Preparation and characterization of a novel amphiphilic nanocarrier based on enzymatic polymerization-derived α-1,3-glucan for efficient quercetin encapsulation. Colloid Polym Sci. 2024;302(7):1123 [Crossref]


As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge