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Bioimpacts. 2018;8(2): 139-151. doi: 10.15171/bi.2018.16
PMID: 29977835        PMCID: PMC6026528

Review

An update of the recombinant protein expression systems of Cyanovirin-N and challenges of preclinical development

Hajie Lotfi 1,2, Roghayeh Sheervalilo 3, Nosratollah Zarghami 1,2 *

Cited by CrossRef: 19

1- Rosales-Mendoza S, García-Silva I, González-Ortega O, Sandoval-Vargas J, Malla A, Vimolmangkang S. The Potential of Algal Biotechnology to Produce Antiviral Compounds and Biopharmaceuticals. Molecules. 2020;25(18):4049 [Crossref]
2- Mazur-Marzec H, Cegłowska M, Konkel R, Pyrć K. Antiviral Cyanometabolites—A Review. Biomolecules. 2021;11(3):474 [Crossref]
3- Ouchida T, Maeda H, Akamatsu Y, Maeda M, Takamatsu S, Kondo J, Misaki R, Kamada Y, Ueda M, Ueda K, Miyoshi E. The specific core fucose-binding lectin Pholiota squarrosa lectin (PhoSL) inhibits hepatitis B virus infection in vitro. Sci Rep. 2023;13(1) [Crossref]
4- Xavier G, Lima Farias de Sousa A, Queiroz dos Santos L, Aguiar D, Gonçalves E, Santos Siqueira A. Structural and functional analysis of Cyanovirin-N homologs: Carbohydrate binding affinities and antiviral potential of cyanobacterial peptides. Journal of Molecular Graphics and Modelling. 2024;129:108718 [Crossref]
5- Cegłowska M, Szubert K, Grygier B, Lenart M, Plewka J, Milewska A, Lis K, Szczepański A, Chykunova Y, Barreto-Duran E, Pyrć K, Kosakowska A, Mazur-Marzec H. Pseudanabaena galeata CCNP1313—Biological Activity and Peptides Production. Toxins. 2022;14(5):330 [Crossref]
6- Gondim A, Roberta da Silva S, Mathys L, Noppen S, Liekens S, Holanda Sampaio A, Nagano C, Renata Costa Rocha C, Nascimento K, Cavada B, Sadler P, Balzarini J. Potent antiviral activity of carbohydrate-specific algal and leguminous lectins from the Brazilian biodiversity. Med Chem Commun. 2019;10(3):390 [Crossref]
7- Salmany N, Lotfi H, Keyhanmanesh R, Ghiasi R. An Overview of Potential Applications for Nanotechnology, Probiotics, and Medicinal Plants in Infertility Problems. CWHR. 2023;19(4) [Crossref]
8- Khalifa S, Shedid E, Saied E, Jassbi A, Jamebozorgi F, Rateb M, Du M, Abdel-Daim M, Kai G, Al-Hammady M, Xiao J, Guo Z, El-Seedi H. Cyanobacteria—From the Oceans to the Potential Biotechnological and Biomedical Applications. Marine Drugs. 2021;19(5):241 [Crossref]
9- BESEDNOVA N, ANDRYUKOV B, ZAPOROZHETS T, ERMAKOVA S, KUZNETSOVA T, KRYZHANOVSKY S, SHCHELKANOV M. Enveloped Viruses: Pathogenetic Targets for Cyanobacterial Lectins. A&Ch. 2022;67(5-6):39 [Crossref]
10- Pagarete A, Ramos A, Puntervoll P, Allen M, Verdelho V. Antiviral Potential of Algal Metabolites—A Comprehensive Review. Marine Drugs. 2021;19(2):94 [Crossref]
11- Loffredo M, Nencioni L, Mangoni M, Casciaro B. Antimicrobial peptides for novel antiviral strategies in the current post‐COVID‐19 pandemic. Journal of Peptide Science. 2024;30(1) [Crossref]
12- Karimi Hajishore N, Abbasi E, Shirvaliloo M, Rasouli R, Mohammad Najjar M, Akbarzadeh A, Sheervalilou R, Nezami Asl A. Application of nanotechnology in removing laboratory contaminants from the environment. Toxin Reviews. 2024;43(2):179 [Crossref]
13- Alvarez C, Félix C, Lemos M. The Antiviral Potential of Algal Lectins. Marine Drugs. 2023;21(10):515 [Crossref]
14- Rotter A, Barbier M, Bertoni F, Bones A, Cancela M, Carlsson J, Carvalho M, Cegłowska M, Chirivella-Martorell J, Conk Dalay M, Cueto M, Dailianis T, Deniz I, Díaz-Marrero A, Drakulovic D, Dubnika A, Edwards C, Einarsson H, Erdoǧan A, Eroldoǧan O, Ezra D, Fazi S, FitzGerald R, Gargan L, Gaudêncio S, Gligora Udovič M, Ivošević DeNardis N, Jónsdóttir R, Kataržytė M, Klun K, Kotta J, Ktari L, Ljubešić Z, Lukić Bilela L, Mandalakis M, Massa-Gallucci A, Matijošytė I, Mazur-Marzec H, Mehiri M, Nielsen S, Novoveská L, Overlingė D, Perale G, Ramasamy P, Rebours C, Reinsch T, Reyes F, Rinkevich B, Robbens J, Röttinger E, Rudovica V, Sabotič J, Safarik I, Talve S, Tasdemir D, Theodotou Schneider X, Thomas O, Toruńska-Sitarz A, Varese G, Vasquez M. The Essentials of Marine Biotechnology. Front Mar Sci. 2021;8 [Crossref]
15- Agarwal R, Trivedi J, Mitra D. High yield production of recombinant cyanovirin-N (antiviral lectin) exhibiting significant anti-HIV activity, from a rationally selected Escherichia coli strain. Process Biochemistry. 2020;93:1 [Crossref]
16- Carpine R, Sieber S. Antibacterial and antiviral metabolites from cyanobacteria: Their application and their impact on human health. Current Research in Biotechnology. 2021;3:65 [Crossref]
17- Al-Khayri J, Asghar W, Khan S, Akhtar A, Ayub H, Khalid N, Alessa F, Al-Mssallem M, Rezk A, Shehata W. Therapeutic Potential of Marine Bioactive Peptides against Human Immunodeficiency Virus: Recent Evidence, Challenges, and Future Trends. Marine Drugs. 2022;20(8):477 [Crossref]

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
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