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Bioimpacts. 2018;8(1): 39-52. doi: 10.15171/bi.2018.06
PMID: 29713601        PMCID: PMC5915707

Original Research

A novel B- and helper T-cell epitopes-based prophylactic vaccine against Echinococcus granulosus

Mohammad Mostafa Pourseif, Gholamali Moghaddam * , Hossein Daghighkia, Ahmad Nematollahi, Yadollah Omidi * ORCID

Cited by CrossRef: 15

1- Xu Z, Tang H, Zhang T, Sun M, Han Q, Xu J, Wei M, Yu Z. TEX19 promotes ovarian carcinoma progression and is a potential target for epitope vaccine immunotherapy. Life Sciences. 2020;241:117171 [Crossref]
2- Mohammadzadeh R, Soleimanpour S, Pishdadian A, Farsiani H. Designing and development of epitope-based vaccines againstHelicobacter pylori. Critical Reviews in Microbiology. 2022;48(4):489 [Crossref]
3- Dehghani J, Adibkia K, Movafeghi A, Maleki-Kakelar H, Saeedi N, Omidi Y. Towards a new avenue for producing therapeutic proteins: Microalgae as a tempting green biofactory. Biotechnology Advances. 2020;40:107499 [Crossref]
4- Pourseif M, Masoudi-Sobhanzadeh Y, Azari E, Parvizpour S, Barar J, Ansari R, Omidi Y. Self-amplifying mRNA vaccines: Mode of action, design, development and optimization. Drug Discovery Today. 2022;27(11):103341 [Crossref]
5- Pourseif M, Yousefpour M, Aminianfar M, Moghaddam G, Nematollahi A. A multi-method and structure-based in silico vaccine designing against Echinococcus granulosus through investigating enolase protein. Bioimpacts. 2019;9(3):131 [Crossref]
6- Dong C, Qin Y, Ma J, Cui W, Chen X, Hou L, Chen X, God’spower B, Eliphaz N, Qin J, Guo W, Ding W, Li Y. The Active Ingredients Identification and Antidiarrheal Mechanism Analysis of Plantago asiatica L. Superfine Powder. Front Pharmacol. 2021;11 [Crossref]
7- Majidiani H, Pourseif M, Kordi B, Sadeghi M, Najafi A. TgVax452, an epitope-based candidate vaccine targeting Toxoplasma gondii tachyzoite-specific SAG1-related sequence (SRS) proteins: immunoinformatics, structural simulations and experimental evidence-based approaches. BMC Infect Dis. 2024;24(1) [Crossref]
8- Asgharzadeh M, Pourseif M, Barar J, Eskandani M, Jafari Niya M, Mashayekhi M, Omidi Y. Functional expression and impact of testis-specific gene antigen 10 in breast cancer: a combined in vitro and in silico analysis. Bioimpacts. 2019;9(3):145 [Crossref]
9- Yang J, Lv Y, Zhu Y, Song J, Zhu M, Wu C, Fu Y, Zhao W, Zhao Y. Optimizing sheep B-cell epitopes in Echinococcus granulosus recombinant antigen P29 for vaccine development. Front Immunol. 2024;15 [Crossref]
10- Pourseif M, Moghaddam G, Nematollahi A, Khordadmehr M, Naghili B, Dehghani J, Omidi Y. Vaccination with rEGVac elicits immunoprotection against different stages of Echinococcus granulosus life cycle: A pilot study. Acta Tropica. 2021;218:105883 [Crossref]
11- Simay S, Akbarzadeh-Khiavi M, Pourseif M, Barar J, Safary A, Omidi Y. Recombinant production and characterization of L-glutaminase (glsA) as a promiscuity therapeutic enzyme. Appl Microbiol Biotechnol. 2022;106(17):5511 [Crossref]
12- Zhang T, Lv Y, Zhao Y, Yang J, Qian B, Zhu Y, Zhao W, Zhu M. Changes in intestinal flora of mice induced by rEg.P29 epitope peptide vaccines. Immunity Inflam & Disease. 2023;11(11) [Crossref]
13- Ponne S, Kumar R, Vanmathi S, Brilhante R, Kumar C. Reverse engineering protection: A comprehensive survey of reverse vaccinology-based vaccines targeting viral pathogens. Vaccine. 2024;42(10):2503 [Crossref]
14- Fan Y, He Y, Li Y, Yin Z, Shi J, Tian T, Shang K, Shi H, Zhang F, Wen H. Design of a novel EmTSP-3 and EmTIP based multi-epitope vaccine against Echinococcus multilocularis infection. Front Immunol. 2024;15 [Crossref]
15- Parvizpour S, Pourseif M, Razmara J, Rafi M, Omidi Y. Epitope-based vaccine design: a comprehensive overview of bioinformatics approaches. Drug Discovery Today. 2020;25(6):1034 [Crossref]
16- Masoudi-Sobhanzadeh Y, Jafari B, Parvizpour S, Pourseif M, Omidi Y. A novel multi-objective metaheuristic algorithm for protein-peptide docking and benchmarking on the LEADS-PEP dataset. Computers in Biology and Medicine. 2021;138:104896 [Crossref]
17- Yu M, Zhu Y, Li Y, Chen Z, Sha T, Li Z, Zhang F, Ding J. Design of a Novel Multi-Epitope Vaccine Against Echinococcus granulosus in Immunoinformatics. Front Immunol. 2021;12 [Crossref]
18- Mora-Ochoa Y, Ramirez-Cando L. Salmonella pathogenesis-based In-silico design and immunoinformatic analysis of multi-epitope vaccine constructs in broiler veterinary medicine. The Veterinary Journal. 2024;308:106240 [Crossref]
19- Parvizpour S, Razmara J, Pourseif M, Omidi Y. In silico design of a triple-negative breast cancer vaccine by targeting cancer testis antigens. Bioimpacts. 2018;9(1):45 [Crossref]
20- Bu Y, Jia C, Tian X, Aimulajiang K, Memon M, Yan R, Song X, Xu L, Li X. Immunization of Goats with Recombinant Protein 14-3-3 Isoform 2(rHcftt-2) Induced Moderate Protection against Haemonchus contortus Challenge. Pathogens. 2020;9(1):46 [Crossref]
21- Chen Z, Zhu Y, Sha T, Li Z, Li Y, Zhang F, Ding J. Design of a new multi-epitope vaccine against Brucella based on T and B cell epitopes using bioinformatics methods. Epidemiol Infect. 2021;149 [Crossref]

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
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