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Bioimpacts. 2019;9(1): 37-43. doi: 10.15171/bi.2019.05
PMID: 30788258        PMCID: PMC6378101

Original Research

Preparation and characterization of biocomposite films of carrageenan/locust bean gum/montmorrillonite for transdermal delivery of curcumin

Ramanjot Kaur 1, Ameya Sharma 1, Vivek Puri 1, Inderbir Singh 1 *

Cited by CrossRef: 26


1- Dogaru B, Simionescu B, Popescu M. Synthesis and characterization of κ-carrageenan bio-nanocomposite films reinforced with bentonite nanoclay. International Journal of Biological Macromolecules. 2020;154:9 [Crossref]
2- Parhi R, Sahoo S, Das A. Applications of polysaccharides in topical and transdermal drug delivery: A recent update of literature. Braz J Pharm Sci. 2022;58 [Crossref]
3- Yadav D, Sonkar K, Kumar J, Chaudhary A. Designing drug delivery systems through additive manufacturing. EJPPS. 2023; [Crossref]
4- Noreen S, Ma J, Saeed M, Pervaiz F, Hanif M, Ahmed B, Farooq M, Akram F, Safdar M, Madni A, Naveed M, Chang-Xing L. Natural polysaccharide-based biodegradable polymeric platforms for transdermal drug delivery system: a critical analysis. Drug Deliv and Transl Res. 2022;12(11):2649 [Crossref]
5- Sharma A, Mittal A, Puri V, Kumar P, Singh I. Curcumin-loaded, alginate–gelatin composite fibers for wound healing applications. 3 Biotech. 2020;10(11) [Crossref]
6- Merg C, Reolon J, Rechia G, Cruz L. Locust bean gum hydrogels are bioadhesive and improve indole-3-carbinol cutaneous permeation: influence of the polysaccharide concentration. Braz J Pharm Sci. 2023;59 [Crossref]
7- Bhatt A, Nainwal N, Purohit P. The Impact of Carrageenan on Pharmascience. CTM. 2024;10(6) [Crossref]
8- Manna S, Jana S. Marine Polysaccharides in Tailor-made Drug Delivery. CPD. 2022;28(13):1046 [Crossref]
9- Terzopoulou Z, Michopoulou A, Palamidi A, Koliakou E, Bikiaris D. Preparation and Evaluation of Collagen-Based Patches as Curcumin Carriers. Polymers. 2020;12(10):2393 [Crossref]
10- Sabbagh F, Kim B. Recent advances in polymeric transdermal drug delivery systems. Journal of Controlled Release. 2022;341:132 [Crossref]
11- Sharma A, Dheer D, Singh I, Puri V, Kumar P. Phytoconstituent-Loaded Nanofibrous Meshes as Wound Dressings: A Concise Review. Pharmaceutics. 2023;15(4):1058 [Crossref]
12- Kongkwamcharoen C, Itharat A, Ketjinda W, Lee H, Moon G, Davies N. Formulation design and physicochemical evaluation of an anti-inflammatory hydrogel patch containing Crinum asiaticum L. extract. 2023;18(3):244 [Crossref]
13- Notario-Pérez F, Cazorla-Luna R, Martín-Illana A, Galante J, Ruiz-Caro R, das Neves J, Veiga M. Design, fabrication and characterisation of drug-loaded vaginal films: State-of-the-art. Journal of Controlled Release. 2020;327:477 [Crossref]
14- P. A, P. A, M. R, Joy J, Mathew S. Developmental prospects of carrageenan-based wound dressing films: Unveiling techno-functional properties and freeze-drying technology for the development of absorbent films — A review. International Journal of Biological Macromolecules. 2024;276:133668 [Crossref]
15- Sabbagh F, Kim B. Microneedles for transdermal drug delivery using clay-based composites. Expert Opinion on Drug Delivery. 2022;19(9):1099 [Crossref]
16- Akhtar N, Singh V, Yusuf M, Khan R. Non-invasive drug delivery technology: development and current status of transdermal drug delivery devices, techniques and biomedical applications. 2020;65(3):243 [Crossref]
17- Tudu M, Samanta A. Natural polysaccharides: Chemical properties and application in pharmaceutical formulations. European Polymer Journal. 2023;184:111801 [Crossref]
18- Genecya G, Adhika D, Adhika W, Wungu T. Optimization of mechanical properties of carrageenan-based bioplastic as food packaging. IOP Conf Ser: Earth Environ Sci. 2023;1201(1):012079 [Crossref]
19- Abd El‑Fattah M, El-Demerdash A, Eassa H, Mohammed K, Khalil I, Esmaeil A, Abdel Aziz S, Amin O. In vitro and in vivo evaluation of crosslinked wound dressing loaded with combined rosuvastatin calcium and levofoxacin simultaneously determined by eco-friendly spectrophotometric method. Futur J Pharm Sci. 2024;10(1) [Crossref]
20- Mohd Zaid N, Sekar M, Bonam S, Gan S, Lum P, Begum M, Mat Rani N, Vaijanathappa J, Wu Y, Subramaniyan V, Fuloria N, Fuloria S. Promising Natural Products in New Drug Design, Development, and Therapy for Skin Disorders: An Overview of Scientific Evidence and Understanding Their Mechanism of Action. DDDT. 2022;Volume 16:23 [Crossref]
21- Chopra H, Bibi S, Kumar S, Khan M, Kumar P, Singh I. Preparation and Evaluation of Chitosan/PVA Based Hydrogel Films Loaded with Honey for Wound Healing Application. Gels. 2022;8(2):111 [Crossref]
22- Puri V, Nagpal M, Singh I, Singh M, Dhingra G, Huanbutta K, Dheer D, Sharma A, Sangnim T. A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges. Nutrients. 2022;14(21):4637 [Crossref]
23- Saccol C, Cervi V, Blume J, Menezes Á, Apel M, da Rosa L, Tasca T, Cruz L. Xanthan-carrageenan film containing sesame seed oil: A nanocomposite pharmaceutical platform for trichomoniasis treatment. International Journal of Biological Macromolecules. 2024;257:128701 [Crossref]
24- Malviya R, Tyagi A, Fuloria S, Subramaniyan V, Sathasivam K, Sundram S, Karupiah S, Chakravarthi S, Meenakshi D, Gupta N, Sekar M, Sudhakar K, Fuloria N. Fabrication and Characterization of Chitosan—Tamarind Seed Polysaccharide Composite Film for Transdermal Delivery of Protein/Peptide. Polymers. 2021;13(9):1531 [Crossref]
25- Henrique Marcondes Sari M, Mota Ferreira L, Cruz L. The use of natural gums to produce nano-based hydrogels and films for topical application. International Journal of Pharmaceutics. 2022;626:122166 [Crossref]
26- Giuliani L, Pegoraro N, Camponogara C, Osmari B, de Bastos Brum T, Reolon J, Rechia G, Oliveira S, Cruz L. Locust bean gum-based hydrogel containing nanocapsules for 3,3′-diindolylmethane delivery in skin inflammatory conditions. Journal of Drug Delivery Science and Technology. 2022;78:103960 [Crossref]
27- Chen Y, Guo J, Alamri A, Alhomrani M, Huang Z, Zhang W. Recent research progress on locust bean gum (LBG)-based composite films for food packaging. Carbohydrate Polymers. 2025;348:122815 [Crossref]


As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge