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Bioimpacts. 2020;10(1): 27-36. doi: 10.15171/bi.2020.04
PMID: 31988854        PMCID: PMC6977588

Original Research

PEGylated gold nanoparticles-ribonuclease induced oxidative stress and apoptosis in colorectal cancer cells

Mostafa Akbarzadeh Khiavi 1,2 ORCID, Azam Safary 2,3 ORCID, Jaleh Barar 2,4 ORCID, Hamed Farzi-Khajeh 5, Abolfazl Barzegari 2, Rahimeh Mousavi 2, Mohammad Hossein Somi 1 * ORCID, Yadollah Omidi 2,4 * ORCID

Cited by CrossRef: 26

1- Moradi A, Pourseif M, Jafari B, Parvizpour S, Omidi Y. Nanobody-based therapeutics against colorectal cancer: Precision therapies based on the personal mutanome profile and tumor neoantigens. Pharmacological Research. 2020;156:104790 [Crossref]
2- Sobhani-Nasab A, Banafshe H, Atapour A, Khaksary Mahabady M, Akbari M, Daraei A, Mansoori Y, Moradi Hasan-Abad A. The use of nanoparticles in the treatment of infectious diseases and cancer, dental applications and tissue regeneration: a review. Front Med Technol. 2024;5 [Crossref]
3- Akbarzadeh-Khiavi M, Torabi M, Olfati A, Rahbarnia L, Safary A. Bio-nano scale modifications of melittin for improving therapeutic efficacy. Expert Opinion on Biological Therapy. 2022;22(7):895 [Crossref]
4- Liu X, Wang J, Ashby C, Zeng L, Fan Y, Chen Z. Gold nanoparticles: synthesis, physiochemical properties and therapeutic applications in cancer. Drug Discovery Today. 2021;26(5):1284 [Crossref]
5- Akbarzadeh-Khiavi M, Farzi-Khajeh H, Somi M, Safary A, Barar J, Ansari R, Omidi Y. Eradication of KRAS mutant colorectal adenocarcinoma by PEGylated gold nanoparticles-cetuximab conjugates through ROS-dependent apoptosis. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2022;653:129890 [Crossref]
6- Faris P. Verbascum ponticum (Stef.) Extract Induces Lung Cancer Apoptosis via Mitochondrial-Dependent Apoptosis Pathway. Life. 2024;14(11):1520 [Crossref]
7- Roshani M, Rezaian-Isfahni A, Lotfalizadeh M, Khassafi N, Abadi M, Nejati M. Metal nanoparticles as a potential technique for the diagnosis and treatment of gastrointestinal cancer: a comprehensive review. Cancer Cell Int. 2023;23(1) [Crossref]
8- Najafi A, Keykhaee M, Kazemi M, Karimi M, Khorramdelazad H, Aghamohamadi N, Bolouri M, Ghaffari-Nazari H, Mirsharif E, Karimi M, Dehghan Manshadi H, Mahdavi S, Safari E, Jalali S, Falak R, Khoobi M. Catalase-gold nanoaggregates manipulate the tumor microenvironment and enhance the effect of low-dose radiation therapy by reducing hypoxia. Biomedicine & Pharmacotherapy. 2023;167:115557 [Crossref]
9- Aula S, Lakkireddy S, Kapley A, Hebalkar N, Sharma R, Uppin S, Jamil K. Evaluation of Biological Effects and Toxicity of Cetyltrimethylammonium Bromide Stabilized Silver Nanoparticles and Cetyltrimethylammonium Bromide Alone Following Intravenous Injection in Mice. CNANOM. 2021;11(1):70 [Crossref]
10- Ghorbani F, Kokhaei P, Ghorbani M, Eslami M. Application of different nanoparticles in the diagnosis of colorectal cancer. Gene Reports. 2020;21:100896 [Crossref]
11- Hashemzadeh N, Dolatkhah M, Aghanejad A, Barzegar-Jalali M, Omidi Y, Adibkia K, Barar J. Folate Receptor-Mediated Delivery of 1-MDT-Loaded Mesoporous Silica Magnetic Nanoparticles to Target Breast Cancer Cells. Nanomedicine (Lond). 2021;16(24):2137 [Crossref]
12- Pham-Nguyen O, Shin J, Park Y, Jin S, Kim S, Jung Y, Yoo H. Fluorescence-Shadowing Nanoparticle Clusters for Real-Time Monitoring of Tumor Progression. Biomacromolecules. 2022;23(8):3130 [Crossref]
13- Xu J, Xu Y, Sun L, Lu B, Yan X, Wang Z, Zhang T. Glucose oxidase loaded Cu2+ based metal-organic framework for glutathione depletion/reactive oxygen species elevation enhanced chemotherapy. Biomedicine & Pharmacotherapy. 2021;141:111606 [Crossref]
14- Zhang L, Zhai B, Wu Y, Wang Y. Recent progress in the development of nanomaterials targeting multiple cancer metabolic pathways: a review of mechanistic approaches for cancer treatment. Drug Delivery. 2023;30(1):1 [Crossref]
15- Guda A, Kirichkov M, Shapovalov V, Muravlev A, Pashkov D, Guda S, Bagliy A, Soldatov S, Chapek S, Soldatov A. Machine Learning Analysis of Reaction Parameters in UV-Mediated Synthesis of Gold Nanoparticles. J Phys Chem C. 2023;127(2):1097 [Crossref]
16- Kiani Nejad Z, Akbar Khandar A, Khatamian M. Graphene quantum dots based MnFe2O4@SiO2 magnetic nanostructure as a pH-sensitive fluorescence resonance energy transfer (FRET) system to enhance the anticancer effect of the drug. International Journal of Pharmaceutics. 2022;628:122254 [Crossref]
17- Sanati M, Afshari A, Kesharwani P, Sukhorukov V, Sahebkar A. Recent trends in the application of nanoparticles in cancer therapy: The involvement of oxidative stress. Journal of Controlled Release. 2022;348:287 [Crossref]
18- Kumar A, Pramanik J, Batta K, Bamal P, Gaur M, Rustagi S, Prajapati B, Bhattacharya S. Impact of metallic nanoparticles on gut microbiota modulation in colorectal cancer: A review. Cancer Innovation. 2024;3(6) [Crossref]
19- Mundekkad D, Cho W. Nanoparticles in Clinical Translation for Cancer Therapy. IJMS. 2022;23(3):1685 [Crossref]
20- Priyadarshi N, Ambule M, Kaushal S, Kumar A, Sagar P, Srivastava A, Singhal N. Nanoglycocluster based diagnostic platform for colorimetric detection of bacteria; A comparative study analysing the effect of AuNPs size, linker length, and glycan diversity. Biosensors and Bioelectronics. 2022;201:113969 [Crossref]
21- Entezari M, Yousef Abad G, Sedghi B, Ettehadi R, Asadi S, Beiranvand R, Haratian N, Karimian S, Jebali A, Khorrami R, Zandieh M, Saebfar H, Hushmandi K, Salimimoghadam S, Rashidi M, Taheriazam A, Hashemi M, Ertas Y. Gold nanostructure-mediated delivery of anticancer agents: Biomedical applications, reversing drug resistance, and stimuli-responsive nanocarriers. Environmental Research. 2023;225:115673 [Crossref]
22- Maddah A, Danesh H, Ziamajidi N, Khosravi H, Abbasalipourkabir R. Oxidative Stress Induction by Gold Nanoparticles in HCT-116 Colon Cancer Cells. Compr Health Biomed Stud. 2024;2(1) [Crossref]

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge