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Bioimpacts. 2020;10(3): 159-167. doi: 10.34172/bi.2020.20
PMID: 32793438        PMCID: PMC7416011

Original Research

Effects of Securigera securidaca (L.) Degen & Dorfl seed extract combined with glibenclamide on paraoxonase1 activity, lipid profile and peroxidation, and cardiovascular risk indices in diabetic rats

Shahin Alizadeh-Fanalou 1 ORCID, Ali Nazarizadeh 1,2 ORCID, Mohammad Babaei 3 ORCID, Mohsen Khosravi 4 ORCID, Navid Farahmandian 1, Elham Bahreini 1 * ORCID

Cited by CrossRef: 6


1- Arab Z, Khayatan D, Razavi S, Zare K, Kheradkhah E, Momtaz S, Ferretti G, Bacchetti T, Sathyapalan T, Emami S, Abdolghaffari A, Sahebkar A. Phytochemicals as Modulators of Paraoxonase-1 in Health and Diseases. Antioxidants. 2022;11(7):1273 [Crossref]
2- Adesina A, Adewuyi A, Otuechere C. Eco-friendly synthesis and assessment of chrysin – primed zinc ferrite nanoparticles against vinyl chloride and 2-acetylaminofluorene model of hepatorenal injury in rats. Results in Chemistry. 2024;7:101524 [Crossref]
3- Mirahmad M, Mohseni S, Tabatabaei-Malazy O, Esmaeili F, Alatab S, Bahramsoltani R, Ejtahed H, Qulami H, Bitarafan Z, Arjmand B, Nazeri E. Antioxidative hypoglycemic herbal medicines with in vivo and in vitro activity against C-reactive protein; a systematic review. Phytomedicine. 2023;109:154615 [Crossref]
4- Khomari F, Kiani B, Alizadeh-Fanalou S, Babaei M, Kalantari-Hesari A, Alipourfard I, Mirzaei F, Yarahmadi S, Bahreini E, Mendoza-Núñez V. Effectiveness of Hydroalcoholic Seed Extract of Securigera securidaca on Pancreatic Local Renin-Angiotensin System and Its Alternative Pathway in Streptozotocin-Induced Diabetic Animal Model. Oxidative Medicine and Cellular Longevity. 2023;2023:1 [Crossref]
5- Nasehi Z, Kheiripour N, Taheri M, Ardjmand A, Jozi F, Aghadavod E, Doustimotlagh A, Shahaboddin M, Siemianowicz K. The Protective Effects of Securigera securidaca Seed Extract on Liver Injury Induced by Bile Duct Ligation in Rats. BioMed Research International. 2022;2022:1 [Crossref]
6- Babaei M, Alizadeh-Fanalou S, Nourian A, Yarahmadi S, Farahmandian N, Nabi-Afjadi M, Alipourfard I, Bahreini E. Evaluation of testicular glycogen storage, FGF21 and LDH expression and physiological parameters of sperm in hyperglycemic rats treated with hydroalcoholic extract of Securigera Securidaca seeds, and Glibenclamide. Reprod Biol Endocrinol. 2021;19(1) [Crossref]
7- Sirca T, Mureșan M, Pallag A, Marian E, Jurca T, Vicaș L, Tunduc I, Manole F, Ștefan L. The Role of Polyphenols in Modulating PON1 Activity Regarding Endothelial Dysfunction and Atherosclerosis. IJMS. 2024;25(5):2962 [Crossref]
8- Li X, Guo D, Chen Y, Hu Y, Zhang F, Jakovljevic V. Complex Coronary Instent Chronic Total Occlusion Lesions: Oxidative Stress, Inflammation, and Coronary Stent Lengths. Oxidative Medicine and Cellular Longevity. 2021;2021:1 [Crossref]
9- Adel-Mehraban M, Tabatabaei-Malazy O, Manayi A, Alatab S, Mohseni S, Fana S, Asili P, Bahramsoltani R, Esmaeili F, Azizi B. Antioxidative and Anti-inflammatory Effects of Plant-derived Hypoglycemic Medicines: An In vivo/In vitro Systematic Review. CTMC. 2024;24(16):1408 [Crossref]


As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge