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BioImpacts. 2021;11(4): 253-261. doi: 10.34172/bi.2021.36
PMID: 34631487        PMCID: PMC8494259

Original Research

Melatonin increases 5-flurouracil-mediated apoptosis of colorectal cancer cells through enhancing oxidative stress and downregulating survivin and XIAP

Ainaz Mihanfar 1, Bahman Yousefi 2, Saber Ghazizadeh Darband 3, Shirin Sadighparvar 4, Mojtaba Kaviani 5, Maryam Majidinia 6 * ORCID

Cited by CrossRef: 0


1- Park S, Ham J, Yang C, Park W, Park H, An G, Song J, Hong T, Park S, Kim H, Song G, Lim W. Melatonin inhibits endometriosis development by disrupting mitochondrial function and regulating tiRNAs. Journal of Pineal Research. 2022; [Crossref]
2- Bedoya-Betancur V, Correa E, Rendón J, Yepes-Pérez A, Cardona-Galeano W, Naranjo T. Chemopreventive Effect on Human Colon Adenocarcinoma Cells of Styrylquinolines: Synthesis, Cytotoxicity, Proapoptotic Effect and Molecular Docking Analysis. Molecules. 2022;27(20):7108 [Crossref]
3- Florido J, Rodriguez-Santana C, Martinez-Ruiz L, López-Rodríguez A, Acuña-Castroviejo D, Rusanova I, Escames G. Understanding the Mechanism of Action of Melatonin, Which Induces ROS Production in Cancer Cells. Antioxidants. 2022;11(8):1621 [Crossref]

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences and provides free editing services. 
Acceptance rate: 24%
First decision: 2-3 days  
Final decision:
3-6 weeks 
Publication fee: Free of charge