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Bioimpacts. 2020;10(4): 259-268. doi: 10.34172/bi.2020.33
PMID: 32983942        PMCID: PMC7502910

Original Research

Designing a new generation of expression toolkits for engineering of green microalgae; robust production of human interleukin-2

Jaber Dehghani 1,2 ORCID, Khosro Adibkia 3 * ORCID, Ali Movafeghi 2, Mohammad M. Pourseif 1, Yadollah Omidi 1,3,4 * ORCID

Cited by CrossRef: 16

1- Leprovost S, Plasson C, Balieu J, Walet‐Balieu M, Lerouge P, Bardor M, Mathieu‐Rivet E. Fine‐tuning the N‐glycosylation of recombinant human erythropoietin using Chlamydomonas reinhardtii mutants. Plant Biotechnology Journal. 2024;22(11):3018 [Crossref]
2- Dehghani J, Balieu J, Perruchon O, Mathieu-Rivet E, Mati-Baouche N, Lerouge P, Bardor M. Exploring protein N-glycosylation in the green microalga Dunaliella salina. Algal Research. 2024;83:103711 [Crossref]
3- Dehghani J, Movafeghi A, Mathieu-Rivet E, Mati-Baouche N, Calbo S, Lerouge P, Bardor M. Microalgae as an Efficient Vehicle for the Production and Targeted Delivery of Therapeutic Glycoproteins against SARS-CoV-2 Variants. Marine Drugs. 2022;20(11):657 [Crossref]
4- Guo L, Yang G. Pioneering DNA assembling techniques and their applications in eukaryotic microalgae. Biotechnology Advances. 2024;70:108301 [Crossref]
5- Goshtasbi H, Okolodkov Y, Movafeghi A, Awale S, Safary A, Barar J, Omidi Y. Harnessing microalgae as sustainable cellular factories for biopharmaceutical production. Algal Research. 2023;74:103237 [Crossref]
6- Sharma P, Goud V, Yamamoto Y, Sahoo L. Efficient Agrobacterium tumefaciens-mediated stable genetic transformation of green microalgae, Chlorella sorokiniana. 3 Biotech. 2021;11(4) [Crossref]
7- Cutolo E, Caferri R, Campitiello R, Cutolo M. The Clinical Promise of Microalgae in Rheumatoid Arthritis: From Natural Compounds to Recombinant Therapeutics. Marine Drugs. 2023;21(12):630 [Crossref]
8- Kumar V, Barwal A, Sharma N, Mir D, Kumar P, Kumar V. Therapeutic proteins: developments, progress, challenges, and future perspectives. 3 Biotech. 2024;14(4) [Crossref]
9- Arshad I, Ahsan M, Zafar I, Sajid M, Sehgal S, Yousaf W, Noor A, Rashid S, Garai S, Moovendhan M, Sharma R. Bioinformatics approaches in upgrading microalgal oil for advanced biofuel production through hybrid ORF protein construction. Biomass Conv Bioref. 2023; [Crossref]
10- Trujillo E, Monreal‐Escalante E, Angulo C. Microalgae‐made human vaccines and therapeutics: A decade of advances. Biotechnology Journal. 2024;19(5) [Crossref]
11- Zhuang H, Ou Y, Chen R, Huang D, Wang C. Comparing the Ability of Secretory Signal Peptides for Heterologous Expression of Anti-Lipopolysaccharide Factor 3 in Chlamydomonas reinhardtii. Marine Drugs. 2023;21(6):346 [Crossref]
12- Castiglia D, Landi S, Esposito S. Advanced Applications for Protein and Compounds from Microalgae. Plants. 2021;10(8):1686 [Crossref]
13- Banerjee A, Ward V. Production of recombinant and therapeutic proteins in microalgae. Current Opinion in Biotechnology. 2022;78:102784 [Crossref]
14- Çakmak R, Uzuner U. Functional and Extracellular Production and Antitumor Activity of Mouse Alpha Klotho in Model Microalga Chlamydomonas reinhardtii. Chemistry & Biodiversity. 2024;21(1) [Crossref]

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge