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Bioimpacts. 2023;13(4): 275-287. doi: 10.34172/bi.2023.26317
PMID: 37645024        PMCID: PMC10460768

Original Article

Preparation and evaluation of a polycaprolactone/chitosan/propolis fibrous nanocomposite scaffold as a tissue engineering skin substitute

Seyedeh-Sara Hashemi 1,2 ORCID, Ali Akbar Mohammadi 1,3 ORCID, Seyedeh-Somayeh Rajabi 4, Parisa Sanati 1,5 ORCID, Alireza Rafati 6 ORCID, Mehdi Kian 2,7 * ORCID, Zahra Zarei 3 * ORCID

Cited by CrossRef: 1


1- Piskláková L, Skuhrovcová K, Bártová T, Seidelmannová J, Vondrovic Š, Velebný V. Trends in the Incorporation of Antiseptics into Natural Polymer-Based Nanofibrous Mats. Polymers. 2024;16(5):664 [Crossref]
2- Satarian F, Ghiyasi Y, Shafiei S, Amiri E, Sharifi E, Esfahani H. Enhanced hemocompatibility and antioxidant efficacy of chitosan-PCL nanofibrous mats with olive oil and honey nika cream for wound healing applications. Journal of Drug Delivery Science and Technology. 2024;100:106138 [Crossref]
3- Mehdikhani M, Yilgör P, Poursamar S, Etemadi N, Gokyer S, Navid S, Farzan M, Farzan M, Babaei M, Rafienia M. A hybrid 3D-printed and electrospun bilayer pharmaceutical membrane based on polycaprolactone/chitosan/polyvinyl alcohol for wound healing applications. International Journal of Biological Macromolecules. 2024;282:136692 [Crossref]
4- Shaabani A, Bizari D, Khoshmohabat H. PEGylated curcumin-loaded poly(vinyl alcohol)/Zwitterionic poly(sulfobetaine vinylimidazole)-grafted chitosan nanofiber as a second-degree burn wound dressing. Carbohydrate Polymers. 2023;321:121307 [Crossref]
5- Hashemi S, Hayatdavoodi Z, Kian M, Nemati N, Mehrabani D, Mohammadi A, Rafati A, Ghaedi M, Ghafari B, Naini A. Evaluation of a Polycaprolactone/Gelatin/Lucilia sericata Larva Extract Nanofibrous Mat for Burn-Wound Healing. Fibers Polym. 2023;24(11):3809 [Crossref]
6- Esmaeili J, Jalise S, Pisani S, Rochefort G, Ghobadinezhad F, Mirzaei Z, Mohammed R, Fathi M, Tebyani A, Nejad Z. Development and characterization of Polycaprolactone/chitosan-based scaffolds for tissue engineering of various organs: A review. International Journal of Biological Macromolecules. 2024;272:132941 [Crossref]
7- Shi T, Liu Y, Wang D, Xia D, Li B, Xu R, Li N, Liang C, Chen M. Spatially engineering tri-layer nanofiber dressings featuring asymmetric wettability for wound healing. Nano Materials Science. 2024; [Crossref]
8- Osanloo M, Noori F, Varaa N, Tavassoli A, Goodarzi A, Moghaddam M, Ebrahimi L, Abpeikar Z, Farmani A, Safaei M, Fereydouni N, Goodarzi A. The wound healing effect of polycaprolactone-chitosan scaffold coated with a gel containing Zataria multiflora Boiss. volatile oil nanoemulsions. BMC Complement Med Ther. 2024;24(1) [Crossref]
9- Hashemi S, Rezaeian R, Rafati A, Sanati P, Mehrabani D, Eshaghi Malekshah R, Moghaddam A, Khonakdar H. A review on application of herbals and their polymer composites in wound healing. Arabian Journal of Chemistry. 2024;17(7):105820 [Crossref]
10- Robles K, Zahra F, Mu R, Giorgio T. Advances in Electrospun Poly(ε-caprolactone)-Based Nanofibrous Scaffolds for Tissue Engineering. Polymers. 2024;16(20):2853 [Crossref]
11- Doodmani S, Bagheri A, Natouri O, Nobakht A, Saghebasl S. Electrospinning-netting of spider-inspired polycaprolactone/collagen nanofiber-nets incorporated with Propolis extract for enhanced wound healing applications. International Journal of Biological Macromolecules. 2024;267:131452 [Crossref]
12- Jaberifard F, Almajidi Y, Arsalani N, Ghorbani M. A self-healing crosslinked-xanthan gum/soy protein based film containing halloysite nanotube and propolis with antibacterial and antioxidant activity for wound healing. International Journal of Pharmaceutics. 2024;656:124073 [Crossref]
13- Gupta P, Sharma S, Jabin S, Jadoun S. Chitosan nanocomposite for tissue engineering and regenerative medicine: A review. International Journal of Biological Macromolecules. 2024;254:127660 [Crossref]


As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge