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Bioimpacts. 2015;5(3): 123-127.
doi: 10.15171/bi.2015.20
PMID: 26457249
PMCID: PMC4597159
Scopus ID: 84944393625
  Abstract View: 3061
  PDF Download: 2120

Perspective

Reliability of malondialdehyde as a biomarker of oxidative stress in psychological disorders

Khalil Ansarin 1, Maryam Khoubnasabjafari 1, Abolghasem Jouyban 2*

1 Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2 Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
*Corresponding Author: Email: ajouyban@hotmail.com

Abstract

Despite very wide variations of malondialdehyde (MDA) concentrations in biological samples, it is still used as a biomarker of oxidative stress in clinical investigations. In the current perspective study, we aimed to summarize a number of critical analytical points for determination of MDA. Technical problems and controversial findings in healthy people and some psychiatric disorders reveal that the reliability of MDA as a biomarker of oxidative stress needs to be re-evaluated by experts.
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Submitted: 11 Jun 2015
ePublished: 23 Aug 2017
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