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Bioimpacts. 2016;6(2): 85-91. doi: 10.15171/bi.2016.12
PMID: 27525225        PMCID: PMC4981253

Original Research

Up-regulation of miR-21 and 146a expression and increased DNA damage frequency in a mouse model of polycystic ovary syndrome (PCOS)

Mohammad Salimi-Asl 1, Hossein Mozdarani 1 * , Mehdi Kadivar 2

Cited by CrossRef: 11


1- Dai B, Jiang J, Huang T. Increased miR-188-3p in Ovarian Granulosa Cells of Patients with Polycystic Ovary Syndrome. Computational and Mathematical Methods in Medicine. 2021;2021:1 [Crossref]
2- Motta A. Epigenetic Marks in Polycystic Ovary Syndrome. CMC. 2020;27(39):6727 [Crossref]
3- Luo M, Huang J, Yang Z, Wang Y, Guo B, Yue Z. Hydroxysafflor yellow A exerts beneficial effects by restoring hormone secretion and alleviating oxidative stress in polycystic ovary syndrome mice. Experimental Physiology. 2020;105(2):282 [Crossref]
4- Ding Y, He P, Li Z. MicroRNA-9119 regulates cell viability of granulosa cells in polycystic ovarian syndrome via mediating Dicer expression. Mol Cell Biochem. 2020;465(1-2):187 [Crossref]
5- Amirhoseiny E, Ganji A, Mosayebi G, Shamsi M, Ghazavi A. Improves immunological and histological alterations associated with Polycystic ovarian syndrome in DHEA -induced mice by Licorice extract. Comp Clin Pathol. 2023;32(5):827 [Crossref]
6- Xu Y, Huang X, Luo Q, Zhang X. MicroRNAs Involved in Oxidative Stress Processes Regulating Physiological and Pathological Responses. MIRNA. 2021;10(3):164 [Crossref]
7- Li S, Song Z, Song M, Qin J, Zhao M, Yang Z. Impaired receptivity and decidualization in DHEA-induced PCOS mice. Sci Rep. 2016;6(1) [Crossref]
8- Lu J, Xue Y, Wang Y, Ding Y, Zou Q, Pan M, Qiao L, Zhang C, Ge Q, Wang T, Li H. RETRACTED ARTICLE: CiRS-126 inhibits proliferation of ovarian granulosa cells through targeting the miR-21-PDCD4-ROS axis in a polycystic ovarian syndrome model. Cell Tissue Res. 2020;381(1):189 [Crossref]
9- Ebrahimi S, Reiisi S, Parchami Barjui S. Increased risk of polycystic ovary syndrome (PCOS) associated with CC genotype of miR-146a gene variation. Gynecological Endocrinology. 2018;34(9):793 [Crossref]
10- Jadideslam G, Ansarin K, Sakhinia E, Babaloo Z, Abhari A, Ghahremanzadeh K, Khalili M, Radmehr R, Kabbazi A. Diagnostic biomarker and therapeutic target applications of miR‐326 in cancers: A systematic review. Journal Cellular Physiology. 2019;234(12):21560 [Crossref]


As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge