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Bioimpacts. 2016;6(3): 135-147. doi: 10.15171/bi.2016.20
PMID: 27853677        PMCID: PMC5108986

Original Research

Reduced graphene oxide decorated with gold nanoparticle as signal amplification element on ultra-sensitive electrochemiluminescence determination of caspase-3 activity and apoptosis using peptide based biosensor

Balal Khalilzadeh 1, Nasrin Shadjou 2, Hadi Afsharan 1, Morteza Eskandani 1, Hojjatollah Nozad Charoudeh 3,4, Mohammad-Reza Rashidi 1,5 *

Cited by CrossRef: 51

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8- Khalilzadeh B, Shadjou N, Kanberoglu G, Afsharan H, de la Guardia M, Charoudeh H, Ostadrahimi A, Rashidi M. Advances in nanomaterial based optical biosensing and bioimaging of apoptosis via caspase-3 activity: a review. Microchim Acta. 2018;185(9) [Crossref]
9- Hasanzadeh M, Baghban H, Shadjou N. Non-enzymatic Determination of L-Proline Amino Acid in Unprocessed Human Plasma Sample Using Hybrid of Graphene Quantum Dots Decorated with Gold Nanoparticles and Poly Cysteine: A Novel Signal Amplification Strategy. ANAL SCI. 2018;34(3):355 [Crossref]
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14- Sharma R. Therapeutic Voyage of Graphene-based Biosensor. LDDD. 2024;21(10):1662 [Crossref]
15- Akbari Nakhjavani S, Khalilzadeh B, Samadi Pakchin P, Saber R, Ghahremani M, Omidi Y. A highly sensitive and reliable detection of CA15-3 in patient plasma with electrochemical biosensor labeled with magnetic beads. Biosensors and Bioelectronics. 2018;122:8 [Crossref]
16- Ognjanović M, Stanković D, Fabián M, Vukadinović A, Prijović Ž, Dojčinović B, Antić B. A Voltammetric Sensor Based on MgFe2O4 Decorated on Reduced Graphene Oxide‐modified Electrode for Sensitive and Simultaneous Determination of Catechol and Hydroquinone. Electroanalysis. 2018;30(11):2620 [Crossref]
17- Rashidiani J, Kamali M, Sedighian H, Akbariqomi M, Mansouri M, Kooshki H. Ultrahigh sensitive enhanced-electrochemiluminescence detection of cancer biomarkers using silica NPs/graphene oxide: A comparative study. Biosensors and Bioelectronics. 2018;102:226 [Crossref]
18- Khalilzadeh B, Rashidi M, Soleimanian A, Tajalli H, Kanberoglu G, Baradaran B, Rashidi M. Development of a reliable microRNA based electrochemical genosensor for monitoring of miR-146a, as key regulatory agent of neurodegenerative disease. International Journal of Biological Macromolecules. 2019;134:695 [Crossref]
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22- Chenaghlou S, Khataee A, Jalili R, Rashidi M, Khalilzadeh B, Woo Joo S. Gold nanostar-enhanced electrochemiluminescence immunosensor for highly sensitive detection of cancer stem cells using CD133 membrane biomarker. Bioelectrochemistry. 2021;137:107633 [Crossref]
23- Khalilzadeh B, Shadjou N, Charoudeh H, Rashidi M. Recent advances in electrochemical and electrochemiluminescence based determination of the activity of caspase-3. Microchim Acta. 2017;184(10):3651 [Crossref]
24- Liu C, Malla P, Wu W, Kabinsing P, Sreearunothai P. Synthesis and Characterization of Au-Decorated Graphene Oxide Nanocomposite for Magneto-Electrochemical Detection of SARS-CoV-2 Nucleocapsid Gene. SSRN Journal. 2023; [Crossref]
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27- Zamanlu M, Eskandani M, Barar J, Jaymand M, Pakchin P, Farhoudi M. Enhanced thrombolysis using tissue plasminogen activator (tPA)-loaded PEGylated PLGA nanoparticles for ischemic stroke. Journal of Drug Delivery Science and Technology. 2019;53:101165 [Crossref]
28- Isildak I, Navaeipour F, Afsharan H, Kanberoglu G, Agir I, Ozer T, Annabi N, Totu E, Khalilzadeh B. Electrochemiluminescence methods using CdS quantum dots in aptamer-based thrombin biosensors: a comparative study. Microchim Acta. 2020;187(1) [Crossref]
29- Xia N, Liu G, Yi X. Surface Plasmon Resonance for Protease Detection by Integration of Homogeneous Reaction. Biosensors. 2021;11(10):362 [Crossref]
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36- Wang Y, Xu Y, Zhao G, Zheng Y, Han Q, Xu X, Ying M, Wang G, Hu Z, Xu H. Utilization of nitrogen self-doped biocarbon derived from soybean nodule in electrochemically sensing ascorbic acid and dopamine. J Porous Mater. 2021;28(2):529 [Crossref]
37- Negahdary M, Angnes L. Electrochemical nanobiosensors equipped with peptides: a review. Microchim Acta. 2022;189(3) [Crossref]
38- Akbari Nakhjavani S, Afsharan H, Khalilzadeh B, Ghahremani M, Carrara S, Omidi Y. Gold and silver bio/nano-hybrids-based electrochemical immunosensor for ultrasensitive detection of carcinoembryonic antigen. Biosensors and Bioelectronics. 2019;141:111439 [Crossref]
39- Vlăsceanu G, Amărandi R, Ioniță M, Tite T, Iovu H, Pilan L, Burns J. Versatile graphene biosensors for enhancing human cell therapy. Biosensors and Bioelectronics. 2018;117:283 [Crossref]
40- Heidari R, Rashidiani J, Abkar M, Taheri R, Moghaddam M, Mirhosseini S, Seidmoradi R, Nourani M, Mahboobi M, Keihan A, Kooshki H. CdS nanocrystals/graphene oxide-AuNPs based electrochemiluminescence immunosensor in sensitive quantification of a cancer biomarker: p53. Biosensors and Bioelectronics. 2019;126:7 [Crossref]
41- Vandghanooni S, Barar J, Eskandani M, Omidi Y. Aptamer-conjugated mesoporous silica nanoparticles for simultaneous imaging and therapy of cancer. TrAC Trends in Analytical Chemistry. 2020;123:115759 [Crossref]
42- Vandghanooni S, Eskandani M. Electrically conductive biomaterials based on natural polysaccharides: Challenges and applications in tissue engineering. International Journal of Biological Macromolecules. 2019;141:636 [Crossref]
43- Majid F, Ali M, Ata S, Bibi I, Malik A, Ali A, Alwadai N, Albalawi H, Shoaib M, Bukhari S, Iqbal M. Fe3O4/graphene oxide/Fe4[Fe(CN)6]3 nanocomposite for high performance electromagnetic interference shielding. Ceramics International. 2021;47(8):11587 [Crossref]
44- Zhao W, Wu M, Mei L, Li H. Ultra-Sensitive Electrochemical Determination of Carcinoembryonic Antigen by a Sandwich Immunosensor Graphene Oxide (GO)-Gold Substrate and a Silver-Coated Bovine Serum Albumin (BSA)-Platinum Nanocomposite on a Glassy Carbon Electrode (GCE). Analytical Letters. 2022;55(6):980 [Crossref]
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47- Luo W, Chu H, Wu X, Ma P, Wu Q, Song D. Disposable biosensor based on novel ternary Ru-PEI@PCN-333(Al) self-enhanced electrochemiluminescence system for on-site determination of caspase-3 activity. Talanta. 2022;239:123083 [Crossref]

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge