Synthesis, characterization and hepatoprotective effect of silymarin phytosome nanoparticles on ethanol-induced hepatotoxicity in rats

Arezoo Gohari Mahmoudabad ^1,2 , Fatemeh Gheybi ³, Mohsen Mehrabi ² * , Alireza Masoudi ⁴, Zeinab Mobasher ⁵, Hamid Vahedi ^6,7, Anneh Mohammad Gharravi ⁸, Fatemeh Sadat Bitaraf ⁹, Seyed Mahdi Rezayat Sorkhabadi ⁵

Cited by CrossRef: 5

1- Rana L, Harwansh R, Deshmukh R. Recent Updates on Phytopharmaceuticals-Based Novel Phytosomal Systems and Their Clinical Trial Status: A Translational Perspective . Crit Rev Ther Drug Carrier Syst. 2025;42(1):1 [Crossref]

2- Al-Sheddi E, Farshori N, Al-Oqail M, Alblwi F, Ahmad J, Al-Khedhairy A, Siddiqui M. Hepatoprotective effect of date fruit extract against ethanol-induced apoptosis in human hepatoma (HepG2) cells. Tissue and Cell. 2024;90:102519 [Crossref]

3- Chen Y, Gao T, Bai J, Yu L, Liu Y, Li Y, Zhang W, Niu S, Liu S, Guo J. Ge-Zhi-Jie-Jiu decoction alleviates alcoholic liver disease through multiple signaling pathways. Journal of Ethnopharmacology. 2025;337:118840 [Crossref]

4- Peres B, Procyuk A, Zelencova A, Kauhova I, Aroyan M, Novikova E. Development of Technology of Phytosubstantiation of Silybum marianum L. Fruits as a Component of Complex Therapy of Liver Diseases. Razrabotka i registraciâ lekarstvennyh sredstv. 2023; [Crossref]

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