1. Mode of photoexcited C₆₀ fullerene involvement in potentiating cisplatin toxicity against drug-resistant L1210 cells

Daria Franskevych , Svitlana Prylutska* , Iryna Grynyuk , Ganna Pasichnyk , Liudmyla Drobot , Olga Matyshevska , Uwe Ritter

Bioimpacts. 2019;9(4): 211-217. doi: 10.15171/bi.2019.26

PMCID: PMC6879712 PMID: 31799157 Scopus ID: 85077126162

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Synergic cytotoxic activity of photoexcited C60 fullerene and cisplatin in a low concentration against leukemic L1210 cells resistant to cisplatin was established. The activation of p38 MAP kinase, decrease of mitochondrial membrane potential and L1210R cells accumulation in subG1 phase were found.

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1. Mode of photoexcited C60 fullerene involvement in potentiating cisplatin toxicity against drug-resistant L1210 cells

1. Mode of photoexcited C₆₀ fullerene involvement in potentiating cisplatin toxicity against drug-resistant L1210 cells