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Original Research

1. Mode of photoexcited C60 fullerene involvement in potentiating cisplatin toxicity against drug-resistant L1210 cells
Daria Franskevych ORCID, Svitlana Prylutska* ORCID, Iryna Grynyuk ORCID, Ganna Pasichnyk ORCID, Liudmyla Drobot ORCID, Olga Matyshevska ORCID, Uwe Ritter ORCID
Bioimpacts. 2019;9(4): 211-217. doi: 10.15171/bi.2019.26
PMCID: PMC6879712     PMID: 31799157     Scopus ID: 85077126162    
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Synergic cytotoxic activity of photoexcited C60 fullerene and cisplatin in a low concentration against leukemic L1210 cells resistant to cisplatin was established. The activation of p38 MAP kinase, decrease of mitochondrial membrane potential and L1210R cells accumulation in subG1 phase were found.
Original Research

2. Water-soluble pristine C60 fullerene attenuates acetaminophen-induced liver injury
Halyna Kuznietsova* ORCID, Oksana Lynchak, Natalia Dziubenko, Tetyana Herheliuk, Yuriy Prylutskyy, Volodymyr Rybalchenko, Uwe Ritter
Bioimpacts. 2019;9(4): 227-237. doi: 10.15171/bi.2019.28
PMCID: PMC6879707     PMID: 31799159     Scopus ID: 85077112447    
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Oxidative stress has been suggested the main trigger and pathological mechanism of toxic liver injury. Powerful free radical scavenger ะก60 fullerene diminishes the signs of acute and chronic liver injury and inhibits EGFR expression in liver cells.

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge