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Original Research

1. Effect of Antioxidants and Carbohydrates in Callus Cultures of Taxus brevifolia: Evaluation of Browning, Callus Growth, Total Phenolics and Paclitaxel Production
Ahmad Yari Khosroushahi, Hossein Naderi-Manesh*, Henrik Toft Simonsen*
Bioimpacts. 2011;1(1): 37-45. doi: 10.5681/bi.2011.006
PMCID: PMC3648945     PMID: 23678406     Scopus ID: 84876744622    
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Original Research

2. Establishing the promising role of novel combination of triple therapeutics delivery using polymeric nanoparticles for Triple negative breast cancer therapy
Ranjita Misra* ORCID, Bamadeb Patra, Sudha Varadharaj, Rama Shanker Verma* ORCID
BioImpacts. 2021;11(3): 199-207. doi: 10.34172/bi.2021.27
PMCID: PMC8314031     PMID: 34336608     Scopus ID: 85109081197    
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Formulation of siRNA adsorbed drug loaded cationic PLGA NPs. Treatment of cells with siRNA adsorbed drug loaded cationic NPs leads to endosomal escape of drugs and siRNA, thereby increasing the efficiency of the therapeutic components inducing more cytotoxicity.
Original Research

3. Evaluation of poly (lactic-co-glycolic acid) nanoparticles to improve the therapeutic efficacy of paclitaxel in breast cancer
Laura Cabeza ORCID, Mazen M. El-Hammadi ORCID, Raul Ortiz ORCID, Maria D. Cayero-Otero, Julia Jiménez-López ORCID, Gloria Perazzoli ORCID, Lucia Martin-Banderas ORCID, Jose M. Baeyens ORCID, Consolación Melguizo* ORCID, Jose Prados ORCID
BioImpacts. 2022;12(6): 515-531. doi: 10.34172/bi.2022.23433
PMCID: PMC9809141     PMID: 36644541     Scopus ID: 85140308481    
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These results suggest that our PTX-PLGA NPs could be a suitable strategy for breast cancer therapy, improving antitumor drug efficiency and reducing systemic toxicity without altering its mechanism of action.

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
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