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Original Research
Mozhgan Ghobadi Pour ORCID, Naser Mirazi* ORCID, Hojatollah Alaei, Maryam Radahmadi, Ziba Rajaei, Alireza Monsef Esfahani
Bioimpacts. 2020;10(3): 177-186. doi: 10.34172/bi.2020.22
PMCID: PMC7416014     PMID: 32793440     Scopus ID: 85089309823    
The rat cirrhotic model is made by using thioacetamide hepatotoxin for 18 weeks. The cirrhotic rats treated to some degrees by using lactulose and silymarin known standard drugs for 8 weeks.
Original Article
Arezoo Gohari Mahmoudabad ORCID, Fatemeh Gheybi, Mohsen Mehrabi* ORCID, Alireza Masoudi, Zeinab Mobasher, Hamid Vahedi, Anneh Mohammad Gharravi, Fatemeh Sadat Bitaraf, Seyed Mahdi Rezayat Sorkhabadi
Bioimpacts. 2023;13(4): 301-311. doi: 10.34172/bi.2023.24128
PMCID: PMC10460772     PMID: 37645028     Scopus ID: 85168161377    
Phytosome silymarin nanoparticles effectively improved ethanol-induced liver damage in models of rats with alcoholic liver disease (ALD) and showed higher beneficial effects and less toxicity compared to the bulky form of phytosome silymarin nanoparticles.