1. A multi-method and structure-based in silico vaccine designing against Echinococcus granulosus through investigating enolase protein

Mohammad Mostafa Pourseif, Mitra Yousefpour*, Mohammad Aminianfar, Gholamali Moghaddam, Ahmad Nematollahi

Bioimpacts. 2019;9(3): 131-144. doi: 10.15171/bi.2019.18

PMCID: PMC6726745 PMID: 31508329 Scopus ID: 85071191509

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The minigene vaccine construct is designed based on the B and T cell epitopes of E. granulosus enolase protein, and ligands for TLR-2 and TLR-4. The minigene vaccine showed stable properties for proper binding with the Toll-like receptors.

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