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Original Research

1. High efficacy of tamoxifen-loaded L-lysine coated magnetic iron oxide nanoparticles in cell cycle arrest and anti-cancer activity for breast cancer therapy

Soheila Rostami ORCID, Farzaneh Tafvizi* ORCID, Hamid Reza Kheiri Manjili
BioImpacts. 2022;12(4): 301-313. doi: 10.34172/bi.2021.23337
PMCID: PMC9376161     PMID: 35975200     Scopus ID: 85138644192    
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The findings suggest that F-Lys-TMX NPs are more effective and have the potential for cell proliferation inhibition and apoptosis induction compared to the TMX. Hence, F-Lys-TMX NPs can be considered as an anti-cancer agent against MCF-7 breast cancer cells.
Original Research

2. Inhibitory effects of gallic acid on the activity of exosomal secretory pathway in breast cancer cell lines: A possible anticancer impact
Nasrollah Jabbari ORCID, Maryam Feghhi, Omid Esnaashari, Hamid Soraya, Jafar Rezaie* ORCID
BioImpacts. 2022;12(6): 549-559. doi: 10.34172/bi.2022.23489
PMCID: PMC9809134     PMID: 36644548     Scopus ID: 85143387474    
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Treatment of MCF-10a, MCF-7, and MDA-MD-231 cells with Gallic acid resulted in inhibition in the activity of the exosomal secretory pathway. Gallic acid can decrease the expression of genes involved in exosomes biogenesis (Alix and CD63) and secretion (Rab proteins). In addition, Gallic acid can change the expression of autophagy markers (LC3 and P62) in these cells. MVB: multivesicular body.
Original Article

3. Apoptotic effects of human amniotic fluid mesenchymal stem cells conditioned medium on human MCF-7 breast cancer cell line
Roghiyeh Pashaei-Asl ORCID, Maryam Pashaiasl, Esmaeil Ebrahimie, Maryam Lale Ataei, Maliheh Paknejad* ORCID
Bioimpacts. 2023;13(3): 191-206. doi: 10.34172/bi.2022.23813
PMCID: PMC10329748     PMID: 37431479     Scopus ID: 85171327177    
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The application of hAFMSCs-CM, as a therapeutic reagent, can suppress breast cancer cells’ viabilities and induce apoptosis.
Original Article

4.

Enhanced efficacy of breast cancer treatment with etoposide-graphene oxide nanogels: A novel nanomedicine approach
Abbas Asoudeh-Fard ORCID, Milad Mohkam, Asghar Parsaei ORCID, Shadi Asghari ORCID, Antonio Lauto, Fatemeh Khoshnoudi ORCID, Mustafa Mhmood Salman Al-Mamoori ORCID, Mohadeseh Asoudeh-Fard, Hossine Ghasemi Sadabadi, Ahmad Gholami* ORCID
Bioimpacts. 2025;15: 30848 | Published on: 2025 Jun 25. doi: 10.34172/bi.30848
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As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate (2024): 20% 
Publication fee: Free of charge

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