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Original Research

1. Promoter methylation and expression pattern of DLX3, ATF4, and FRA1 genes during osteoblastic differentiation of adipose-derived mesenchymal stem cells
Sevda Rahimzadeh ORCID, Reza Rahbarghazi, Somayeh Aslani, Hadi Rajabi, Zeinab Latifi, Majid Farshdousti Hagh, Alireza Nourazarian, Hojjatollah Nozad Charoudeh, Mohammad Nouri* ORCID, Alireza Abhari* ORCID
Bioimpacts. 2020;10(4): 243-250. doi: 10.34172/bi.2020.31
PMCID: PMC7502906     PMID: 32983940     Scopus ID: 85092056978    
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Adipose-derived mesenchymal stem cells were incubated with osteogenic differentiation medium. RNA and DNA were extracted on days 0, 7, 14 and 21 days of differentiation period. The expression and promoter methylation of DLX3, ATF4, and FRA1 genes were analyzed by real-time polymerase chain reaction and methylation-specific quantitative PCR, respectively
Original Research

2. Osteoblastic cell response to Al2O3-Ti composites as bone implant materials
Marjan Bahraminasab* ORCID, Samaneh Arab, Somaye Ghaffari
BioImpacts. 2022;12(3): 247-259. doi: 10.34172/bi.2021.2330
PMCID: PMC9124877     PMID: 35677667     Scopus ID: 85132130879    
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Our in-vitro findings demonstrated that the 75Ti, 50Ti, and 25Ti composites havehigh potential to be used as load-bearing orthopedic materials.
Original Article

3. Evaluation of osteogenic differentiation of human mesenchymal stem cells (hMSCs) on random and aligned polycaprolactone-polyaniline-gelatin scaffolds
Ali KarbalaeiMahdi ORCID, Kaykhosro Moridi ORCID, Marzieh Ghollasi* ORCID
Bioimpacts. 2023;13(2): 123-132. doi: 10.34172/bi.2022.23713
PMCID: PMC10182442     PMID: 37193074     Scopus ID: 85152111515    
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PCL-PANI-GEL fibers showed to be capable candidates for cell attachment and growth. Furthermore, they proved to be of excellent use in bone tissue differentiation.

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
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