Jean J. Latimer*
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Hossein Daghagh , Haniyeh Rahbar Kafshboran, Yousef Daneshmandpour, Maryam Nasiri Aghdam, Shahrzad Talebian, Jafar Nouri Nojadeh, Hamid Hamzeiy, Saskia Biskup, Ebrahim Sakhinia*
Regarding the inheritance pattern in the family and clinical manifestations in the index patient, we propose that the mentioned variant in the CSF1R gene may cause BANDDOS.
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Roghiyeh Pashaei-Asl , Maryam Pashaiasl, Esmaeil Ebrahimie, Maryam Lale Ataei, Maliheh Paknejad*
The application of hAFMSCs-CM, as a therapeutic reagent, can suppress breast cancer cells’ viabilities and induce apoptosis.
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Forough Alemi , Masomeh Maleki, Mostafa Mir, Abbas Ebrahimi-Kalan, Mojtaba Zarei, Bahman Yousefi* , Nadereh Rashtchizadeh*
In this work, a graphene oxide-based nanoformulation was designed to deliver a high concentration of doxorubicin to osteosarcoma cancer cells. This nanoformulation showed a better release profile in an acidic condition of tumor site, and higher cytotoxicity and apoptosis rate in comparison to free doxorubicin, which suggests, it is a potential platform for targeted therapy of osteosarcoma.
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Zhaohui Liu* , Yanli Meng, Yu Miao, Lili Yu, Qiannan Yu
Our findings could suggest the use of AS for treating lung disorders through a mechanism involving SIRT1 expression.
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Diba Ghasemi , Somayeh Ebrahimi-Barough, Mohammad Hossein Nekoofar, Abdolreza Mohamadnia, Nasrin Lotfibakhshaiesh, Naghmeh Bahrami, Roya Karimi, Vajihe Taghdiri Nooshabadi, Mahmoud Azami, Elham Hasanzadeh, Jafar Ai*
The analysis revealed that after a few days of being encapsulated in alginate hydrogel, hEnSCs may grow into oocyte-like cells at a controlled dosage of RA and BMP4, confirming the biocompatibility and safety of the manufactured alginate hydrogel on these differentiated cells.
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Mina Yousefnezhad, Soodabeh Davaran* , Mirzaagha Babazadeh, Abolfazl Akbarzadeh, Hamidreza Pazoki-Toroudi
Drug repurposing is an effective strategy for identifying and using approved drugs for new therapeutic purposes. We investigated co-delivery of the antitumor drugs, doxorubicin (DOX), and ezetimibe (EZ) as a cholesterol uptake-blocking drug with PCEC on prostate cancer cell line (PC3).
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Mitra Torabi , Ayuob Aghanejad*, Pouria Savadi , Abolfazl Barzegari, Yadollah Omidi , Jaleh Barar*
Owing to their unique advantages, mesoporous silica nanoparticles (MSNPs) have attracted much attention for drug delivery and targeting. In the current study, MSNPs were fabricated, PEGylated, loaded with sunitinib, and conjugated with mucin-16 aptamer to target CA125 on ovarian cancer cells.
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