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Letter to the Editor
Morteza Mahmoudi* ORCID, Sherry Moss ORCID, Loraleigh Keashly
Bioimpacts. 2022;12(1): 1-2. doi: 10.34172/bi.2021.44
PMCID: PMC8783085     PMID: 35087710     Scopus ID: 85127200632    
Dr. Morteza Mahmoudi is an Assistant Professor of Radiology and Precision Health Program at Michigan State University (MSU). His specific research interest is in nanomedicine and regenerative medicine for the development of new nano-based platforms for prevention/treatment of life-threatening conditions.
Mini Review
Mohammad A. Rafi* ORCID
Bioimpacts. 2022;12(1): 3-7. doi: 10.34172/bi.2021.23931
PMCID: PMC8783082     PMID: 35087711     Scopus ID: 85127157009    
Cutting viral dose in half or using BM cells from heterozygote mice in a combination of BMT and gene therapy treatments result in a similar reduction in lifespan of the treated mice.
Review
Luigi X Cubeddu* ORCID, Daisy de la Rosa, Michele Ameruoso
Bioimpacts. 2022;12(1): 9-20. doi: 10.34172/bi.2021.23630
PMCID: PMC8783084     PMID: 35087712     Scopus ID: 85127123894    
A combination of old age, comorbidities, increased cytokine levels and proarrhythmic drug therapies canexplain the increased arrhythmic events reported in severe COVID-19 disease.
Original Research
Fatemeh Khonsari ORCID, Mostafa Heydari ORCID, Rassoul Dinarvand ORCID, Mohammad Sharifzadeh ORCID, Fatemeh Atyabi* ORCID
Bioimpacts. 2022;12(1): 21-32. doi: 10.34172/bi.2021.23389
PMCID: PMC8783081     PMID: 35087713     Scopus ID: 85127207881    
Nanostructured-Lipid-Carriers (NLCs) for brain delivery of rapamycin were designed by modification of optimized cationic-NLCs (C-NLC) with different approaches. The targeted transferrin decorated NLCs(Tf-NLCs) in comparison to untargeted bare-NLCs (B-NLCs) showed higher cellular uptake and appropriate targeted accumulation in the brain.
Original Research
Mozhgan Fatahi Dehpahni ORCID, Khosrow Chehri* ORCID, Mehri Azadbakht ORCID
Bioimpacts. 2022;12(1): 33-42. doi: 10.34172/bi.2021.22037
PMCID: PMC8783078     PMID: 35087714     Scopus ID: 85127179595    
Aerobic vaginitis is a mixed infection caused by aerobic bacteria. This type of vaginitis model was established in mice by Escherichia coli and Staphylococcus aureus and evaluated the effect of silver nanoparticles and L carnitine in their treatment.
Original Research
Bambang Kuswandi* ORCID, Nur Andriani, Ari S Nugraha
Bioimpacts. 2022;12(1): 43-50. doi: 10.34172/bi.2021.41
PMCID: PMC8783083     PMID: 35087715     Scopus ID: 85127209198    
A wearable smart woman pad is developed for pH and urea detection in mensuration blood samples that integrated with thread-paper microfluidic devices (μTPAD). Here a threaded part for the whole blood handling, while a paper part for the analyte detection.
Original Research
Nadezhda V. Maksimova ORCID, Anna V. Michenko, Olga A. Krasilnikova ORCID, Ilya D. Klabukov* ORCID, Igor Yu. Gadaev ORCID, Michael E. Krasheninnikov ORCID, Pavel A. Belkov, Aleksey V. Lyundup ORCID
Bioimpacts. 2022;12(1): 51-55. doi: 10.34172/bi.2021.22167
PMCID: PMC8783077     PMID: 35087716     Scopus ID: 85127152579    
Three-year follow-up of patients, treated for diabetic foot ulcers with mesenchymal stromal cells that revealed absence of ulcer recurrence, neoplasms, and scar contracture. Collagen ultrasound density decreased by 57% and the epidermal thickness increased by 72% in the area of healed ulcers.
Original Research
Zahra Olfat Noubari ORCID, Asal Golchin, Marziyeh Fathi* ORCID, Ailar Nakhlband* ORCID
Bioimpacts. 2022;12(1): 57-64. doi: 10.34172/bi.2021.23831
PMCID: PMC8783080     PMID: 35087717     Scopus ID: 85127219250    
The prepared CS-based hydrogels with desired properties including porous structure, high swelling ability, and cytocompatibility did not show oxidative stress for the nesting of stem cells.
Original Research
Efthymia-Iliana Matthaiou ORCID, Yi Guo, Jaleh Barar ORCID, Raphael Sandaltzopoulos, Lana E. Kandalaft, Chunsheng Li*, George Coukos, Yadollah Omidi* ORCID
Bioimpacts. 2022;12(1): 65-86. doi: 10.34172/bi.2021.23511
PMCID: PMC8783079     PMID: 35087718     Scopus ID: 85127176631    
Poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) functionalized with polyethylene glycol (PEG)and anti-TEM1 antibody fragment (78Fc) and loaded with necrosis-inducing agent shikonin (SHK)(78Fc-PLGA-SHK NPs) is a highly effective immunostimulating nanomedicine against theTEM1-expressing cells for targeted therapy of solid tumors.