Zhengmin Liang  , Miaoxuan Li, Jiamin Ni, Tariq Hussain, Jiao Yao, Yinjuan Song, Yiduo Liu, Haoran Wang, Xiangmei Zhou*
CFP10-NPs significantly enhanced the secretion of TNF-α and IL-1β in J774A.1 macrophages. Mucosal immunization with CFP10-NPs significantly increased the levels of TNF-α, IL-1β, IgA and CFP10-specific IFN-γ, and decreased bacterial load in lungs and spleen of M. bovis-infected mice.
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Fatemeh Abedi Jafari , Asghar Abdoli* , Reza Pilehchian, Neda Soleimani, Seyed Masoud Hosseini
The experiment concluded that the C. novyi nontoxic might be a suitable and safe candidate, a novel therapeutic approach to encounter such hypoxic regions in the center of tumors
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Javad Firouzi , Fattah Sotoodehnejadnematalahi, Alireza Shokouhifar , Mahsa Rahimi, Niloufar Sodeifi, Parisa Sahranavardfar, Masoumeh Azimi, Ehsan Janzamin, Majid Safa, Marzieh Ebrahimi*
The effect of silibinin evaluated on self-renewal, tumorgenicity, and metastasis potential of Mammospheres derived from MCF-7, MDA-MB231 cell lines, and MDA-MB468 aggregated cells
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Rana Dizaji , Ali Sharafi, Jalal Pourahmad, Saba Vatanpour, Hossein Dinmohammadi, Hossein Vatanpour, Mir-Jamal Hosseini*
The role of Sirt/AMPK signaling pathway in venom-induced AKI. Mitochondrial biogenesis has a significant effect on fatty acid oxidation and mitochondrial integrity, supporting the key role of Sirt3 and AMPK gene expression and CoQ10 level following venom-induced AKI.
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Hadis Zeinali , Mahnaz Azarnia* , Peyman Keyhanvar* , Reza Moghadasali, Somayeh Ebrahimi-Barough, Majid Marandi-Kouchaki
After extraction and culture, human endometrial stromal / stem cells (hEnSCs) were injected into the caudal vein of male Wistar rats with cisplatin-induced acute renal injury (AKI). Cell injection reduced inflammation and pathological damage and increased kidney cell proliferation.
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Sanaz Javanmardi , Samira Sadat Abolmaali* , Mohammad Javad Mehrabanpour, Mahmoud Reza Aghamaali, Ali Mohammad Tamaddon
miR-21 overexpression can result in down-regulation of the critical inhibitory proteins in tumor cells. Anti-miR-21 delivery to resistant ovary tumor cells using the carboxymethylated PEG5k-polyethylenemine nanohydrogels bearing redox-sensitive crosslinks, knockdown the tumor associated angiogenesis and provoke apoptosis though ROS generation.
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Fatemeh Karami , Behrouz Asgari Abibeiglou, Saghar Pahlavanneshan, Ali Farrokhi, Amin Tamadon, Mohsen Basiri, Keynoosh Khalooghi, Majid Fallahi, Yaser Tahamtani*
miR-21 overexpression can result in down-regulation of the critical inhibitory proteins in tumor cells. Anti-miR-21 delivery to resistant ovary tumor cells using the carboxymethylated PEG5k-polyethylenemine nanohydrogels bearing redox-sensitive crosslinks, knockdown the tumor associated 669 angiogenesis and provoke apoptosis though ROS generation.
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Niloofar Babanejad , Umadevi Kandalam, Yadollah Omidi , Hamid Omidian*
MG63 and GMS Cell exposure to the control PEO and melted PEO (80°C-treated samples) demonstrated no cell toxicity, however cell exposure to 180°C-treated samples exhibited severe cell toxicity that is attributed to the byproducts remained of the PEO thermo-oxidative degradation. Cytotoxicity of the manipulated PEO is independent of its molecular weight.
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Aleksandr L. Urakov* , Natalya A. Urakova
Aleksandr Urakov is a professor, head of the department of General and Clinical Pharmacology at the Izhevsk State Medical Academy (ISMA). His specific research interest is in physical-chemical materials science, pharmacy, and medicine to develop new inventions designed to diagnose, prevent, and treat life-threatening conditions.
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