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Original Research
Fatemeh Rahimi-Sherbaf ORCID, Samad Nadri ORCID, Ali Rahmani, Atousa Dabiri Oskoei* ORCID
Bioimpacts. 2020;10(2): 117-122. doi: 10.34172/bi.2020.14
PMCID: PMC7186541     PMID: 32363155     Scopus ID: 85090604351    
Stem cells has shown different behavior and differentiation pattern due to its microenvironment. The neural differentiation of PMSCs were affected by its substrate. 3D hybrid nanoscaffold has different impact on neural differentiation of PMSCs
Original Research
Sevda Rahimzadeh ORCID, Reza Rahbarghazi, Somayeh Aslani, Hadi Rajabi, Zeinab Latifi, Majid Farshdousti Hagh, Alireza Nourazarian, Hojjatollah Nozad Charoudeh, Mohammad Nouri* ORCID, Alireza Abhari* ORCID
Bioimpacts. 2020;10(4): 243-250. doi: 10.34172/bi.2020.31
PMCID: PMC7502906     PMID: 32983940     Scopus ID: 85092056978    
Adipose-derived mesenchymal stem cells were incubated with osteogenic differentiation medium. RNA and DNA were extracted on days 0, 7, 14 and 21 days of differentiation period. The expression and promoter methylation of DLX3, ATF4, and FRA1 genes were analyzed by real-time polymerase chain reaction and methylation-specific quantitative PCR, respectively
Original Research
Aisha Ishaque ORCID, Irfan Khan, Asmat Salim* ORCID, Rida-e-Maria Qazi, Tuba Shakil Malick, Durriyyah Sharifah Hasan Adli
BioImpacts. 2022;12(2): 147-154. doi: 10.34172/bi.2021.23634
PMCID: PMC8905589     PMID: 35411294     Scopus ID: 85127092191    
Rat bone marrow derived MSCs were cultured and expanded under in-vitro conditions followed by chemical induced differentiation into neuronal lineage (ectodermal origin). However, germ layer transition was observed as the Mix Paired-Like Homeobox MixL1 and T Brachyury genes are over expressed, both genes are responsible for the formation of endoderm and mesoderm layers.
Original Article
Ali KarbalaeiMahdi ORCID, Kaykhosro Moridi ORCID, Marzieh Ghollasi* ORCID
Bioimpacts. 2023;13(2): 123-132. doi: 10.34172/bi.2022.23713
PMCID: PMC10182442     PMID: 37193074     Scopus ID: 85152111515    
PCL-PANI-GEL fibers showed to be capable candidates for cell attachment and growth. Furthermore, they proved to be of excellent use in bone tissue differentiation.
Original Article
Diba Ghasemi ORCID, Somayeh Ebrahimi-Barough, Mohammad Hossein Nekoofar, Abdolreza Mohamadnia, Nasrin Lotfibakhshaiesh, Naghmeh Bahrami, Roya Karimi, Vajihe Taghdiri Nooshabadi, Mahmoud Azami, Elham Hasanzadeh, Jafar Ai* ORCID
Bioimpacts. 2023;13(3): 229-240. doi: 10.34172/bi.2022.23960
PMCID: PMC10329755     PMID: 37431484     Scopus ID: 85170553171    
The analysis revealed that after a few days of being encapsulated in alginate hydrogel, hEnSCs may grow into oocyte-like cells at a controlled dosage of RA and BMP4, confirming the biocompatibility and safety of the manufactured alginate hydrogel on these differentiated cells.
Original Research
Mohammadreza Dastouri* ORCID, Hilal Ozdag ORCID, Ahmet Ruchan Akar ORCID, Alp Can ORCID
Bioimpacts. 2023;13(4): 289-300. doi: 10.34172/bi.2022.24132
PMCID: PMC10460769     PMID: 37645025     Scopus ID: 85168143106    
In this study, we demonstrate a multi-step differential differentiation of iPS cells into EPCs and VSMCs, unlike previous studies in which iPS cells have been induced to differentiate into ECs. Concomitantly, during the differentiation protocol, Myc and Klf4 oncogene expressions were also analyzed from a translational perspective.
Original Article
Duong Thi Thuy Le* ORCID, Cuong Manh Vu ORCID, Thuy Thi Bich Ly, Nam Trung Nguyen, Phuong Thi Mai Nguyen, Ha Hoang Chu
Bioimpacts. 2024;14(1): 27652. doi: 10.34172/bi.2023.27652
PMCID: PMC10844589     PMID: 38327632     Scopus ID: 85182763168    
Original Article
Nahid Rezazadeh ORCID, Effat Alizadeh, Somaieh Soltani, Soodabeh Davaran* ORCID, Neda Esfandiari* ORCID
Bioimpacts. 2024;14(6): 30159. doi: 10.34172/bi.2024.30159
PMCID: PMC11530965     PMID: 39493895     Scopus ID: 85196320454    
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As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
Publication fee: Free of charge