Fatemeh Rahimi-Sherbaf , Samad Nadri , Ali Rahmani, Atousa Dabiri Oskoei*
Stem cells has shown different behavior and differentiation pattern due to its microenvironment. The neural differentiation of PMSCs were affected by its substrate. 3D hybrid nanoscaffold has different impact on neural differentiation of PMSCs
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Sevda Rahimzadeh , Reza Rahbarghazi, Somayeh Aslani, Hadi Rajabi, Zeinab Latifi, Majid Farshdousti Hagh, Alireza Nourazarian, Hojjatollah Nozad Charoudeh, Mohammad Nouri* , Alireza Abhari*
Adipose-derived mesenchymal stem cells were incubated with osteogenic differentiation medium. RNA and DNA were extracted on days 0, 7, 14 and 21 days of differentiation period. The expression and promoter methylation of DLX3, ATF4, and FRA1 genes were analyzed by real-time polymerase chain reaction and methylation-specific quantitative PCR, respectively
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Aisha Ishaque , Irfan Khan, Asmat Salim* , Rida-e-Maria Qazi, Tuba Shakil Malick, Durriyyah Sharifah Hasan Adli
Rat bone marrow derived MSCs were cultured and expanded under in-vitro conditions followed by chemical induced differentiation into neuronal lineage (ectodermal origin). However, germ layer transition was observed as the Mix Paired-Like Homeobox MixL1 and T Brachyury genes are over expressed, both genes are responsible for the formation of endoderm and mesoderm layers.
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Ali KarbalaeiMahdi , Kaykhosro Moridi , Marzieh Ghollasi*
PCL-PANI-GEL fibers showed to be capable candidates for cell attachment and growth. Furthermore, they proved to be of excellent use in bone tissue differentiation.
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Diba Ghasemi , Somayeh Ebrahimi-Barough, Mohammad Hossein Nekoofar, Abdolreza Mohamadnia, Nasrin Lotfibakhshaiesh, Naghmeh Bahrami, Roya Karimi, Vajihe Taghdiri Nooshabadi, Mahmoud Azami, Elham Hasanzadeh, Jafar Ai*
The analysis revealed that after a few days of being encapsulated in alginate hydrogel, hEnSCs may grow into oocyte-like cells at a controlled dosage of RA and BMP4, confirming the biocompatibility and safety of the manufactured alginate hydrogel on these differentiated cells.
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Mohammadreza Dastouri* , Hilal Ozdag , Ahmet Ruchan Akar , Alp Can
In this study, we demonstrate a multi-step differential differentiation of iPS cells into EPCs and VSMCs, unlike previous studies in which iPS cells have been induced to differentiate into ECs. Concomitantly, during the differentiation protocol, Myc and Klf4 oncogene expressions were also analyzed from a translational perspective.
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Duong Thi Thuy Le* , Cuong Manh Vu , Thuy Thi Bich Ly, Nam Trung Nguyen, Phuong Thi Mai Nguyen, Ha Hoang Chu
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Nahid Rezazadeh , Effat Alizadeh, Somaieh Soltani, Soodabeh Davaran* , Neda Esfandiari*
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