Azam Safary ORCID, Mostafa Akbarzadeh-Khiavi ORCID, Jaleh Barar ORCID, Yadollah Omidi* ORCID
Bioimpacts. 2023;13(4): 269-273. doi: 10.34172/bi.2023.27494
PMCID: PMC10460773     PMID: 37645029     Scopus ID: 85168085723    
Professor Yadollah Omidi has a Ph.D. degree in Pharmaceutical Sciences (2003, Cardiff University, UK). He is currently working as a full professorat Nova Southeastern University College of Pharmacy, Florida. He has consecutively been listedamong top 1% highly cited scientists worldwide by WoS-ESI.
Original Article
Seyedeh-Sara Hashemi ORCID, Ali Akbar Mohammadi ORCID, Seyedeh-Somayeh Rajabi, Parisa Sanati ORCID, Alireza Rafati ORCID, Mehdi Kian* ORCID, Zahra Zarei* ORCID
Bioimpacts. 2023;13(4): 275-287. doi: 10.34172/bi.2023.26317
PMCID: PMC10460768     PMID: 37645024     Scopus ID: 85168111465    
An overview of the fabrication process of the polycaprolactone/chitosan/propolis scaffold followed by the characterization of physical, chemical, and biological properties as a proper candidate for dressing skinwounds.
Original Research
Mohammadreza Dastouri* ORCID, Hilal Ozdag ORCID, Ahmet Ruchan Akar ORCID, Alp Can ORCID
Bioimpacts. 2023;13(4): 289-300. doi: 10.34172/bi.2022.24132
PMCID: PMC10460769     PMID: 37645025     Scopus ID: 85168143106    
In this study, we demonstrate a multi-step differential differentiation of iPS cells into EPCs and VSMCs, unlike previous studies in which iPS cells have been induced to differentiate into ECs. Concomitantly, during the differentiation protocol, Myc and Klf4 oncogene expressions were also analyzed from a translational perspective.
Original Article
Arezoo Gohari Mahmoudabad ORCID, Fatemeh Gheybi, Mohsen Mehrabi* ORCID, Alireza Masoudi, Zeinab Mobasher, Hamid Vahedi, Anneh Mohammad Gharravi, Fatemeh Sadat Bitaraf, Seyed Mahdi Rezayat Sorkhabadi
Bioimpacts. 2023;13(4): 301-311. doi: 10.34172/bi.2023.24128
PMCID: PMC10460772     PMID: 37645028     Scopus ID: 85168161377    
Phytosome silymarin nanoparticles effectively improved ethanol-induced liver damage in models of rats with alcoholic liver disease (ALD) and showed higher beneficial effects and less toxicity compared to the bulky form of phytosome silymarin nanoparticles.
Original Article
Yuri Yu. Shchegolev ORCID, Danila V. Sorokin, Alexander M. Scherbakov* ORCID, Olga E. Andreeva ORCID, Diana I. Salnikova ORCID, Ekaterina I. Mikhaevich ORCID, Margarita V. Gudkova ORCID, Mikhail A. Krasil’nikov ORCID
Bioimpacts. 2023;13(4): 313-321. doi: 10.34172/bi.2023.27490
PMCID: PMC10460766     PMID: 37645026     Scopus ID: 85168127787    
Prolonged cell treatment with mTOR inhibitor rapamycin leads to the development of resistance. Exosomes of resistant cells induce the resistance to rapamycin in the parent MCF-7cells. Exosome-induced resistance reproduces the changes revealed in the rapamycin-resistant cells, including the activation of ERK/AP-1.
Original Article
Seyed Esmail Razavi ORCID, Amin Talebi* ORCID
Bioimpacts. 2023;13(4): 323-332. doi: 10.34172/bi.2023.24097
PMCID: PMC10460767     PMID: 37645030     Scopus ID: 85168153678    
In the prolapse model, computational results show incomplete leaflet coaptation,higher MR severity, and also a significant increment of posterior leaflet stress compared to thenormal valve
Original Article
Samaneh Tokhanbigli ORCID, Helia Alavifard ORCID, Hamid Asadzadeh Aghdaei, Mohammad Reza Zali, Kaveh Baghaei* ORCID
Bioimpacts. 2023;13(4): 333-346. doi: 10.34172/bi.2022.24209
PMCID: PMC10460770     PMID: 37645031     Scopus ID: 85154024997    
Combining LY6E loaded DC therapy with pioglitazone improved the DC therapy effect for colorectal cancer treatment. LY6E pulsed DCs excites the CD8 positive immune responses against colorectal models. Pioglitazone inhibits IL-6 axis and formation of CRC cell lines proliferation through IL-6/STAT3 by influencing the immunosuppressive feature of the tumor microenvironment.
Short Communication
Bambang Kuswandi* ORCID, Lukman H Irsyad, Ayik R. Puspaningtyas ORCID
Bioimpacts. 2023;13(4): 347-353. doi: 10.34172/bi.2023.24195
PMCID: PMC10460771     PMID: 37645027     Scopus ID: 85168115042    
A wearable smart pacth is developed for sweat analysis, such as lactic acid, sodium ions, and pH simultaneously that integrated with the cloth-based microfluidic devices (CMDs). Here cotton fabric has been employed as the hydrophilic platform because of its high porosity even without any pretreatment, while the batic (the wax) stamp technology was used for make hydrophobic barriers to guide the sweat flow.