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Original Research

1. CRISPRi-mediated knock-down of PRDM1/BLIMP1 programs central memory differentiation in ex vivo-expanded human T cells

Mohammad Azadbakht ORCID, Ali Sayadmanesh, Naghme Nazer, Amirhossein Ahmadi, Sara Hemmati, Hoda Mohammadzade, Marzieh Ebrahimi, Hossein Baharvand, Babak Khalaj, Mahmoud Reza Aghamaali* ORCID, Mohsen Basiri* ORCID
BioImpacts. 2022;12(4): 337-347. doi: 10.34172/bi.2021.23522
PMCID: PMC9376159     PMID: 35975204     Scopus ID: 85137404752    
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PRDM1/BLIMP1 expression is increased during differentiation from naïve to effector T cell.CRISPRi-mediated suppression of this transcription factor in ex vivo-expanded primary human T cellsresulted in increased central memory phenotype in human T cells.
Review

2. Advance trends in targeting homology-directed repair for accurate gene editing: An inclusive review of small molecules and modified CRISPR-Cas9 systems

Forough Shams ORCID, Hadi Bayat, Omid Mohammadian, Somayeh Mahboudi, Hassan Vahidnezhad, Mohsen Soosanabadi, Azam Rahimpour* ORCID
BioImpacts. 2022;12(4): 371-391. doi: 10.34172/bi.2022.23871
PMCID: PMC9376165     PMID: 35975201     Scopus ID: 85137393658    
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Review

3. CRISPR-based gene editing in plants: Focus on reagents and their delivery tools
Vida Ebrahimi ORCID, Atieh Hashemi* ORCID
Bioimpacts. 2025;15: 30019 | Published on: 2024 Jun 15. doi: 10.34172/bi.30019
PMCID: PMC11830140     PMID: 39963563    
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4. CRISPR-Cas9 in basic and translational aspects of cancer therapy
Maryam Samareh Salavatipour ORCID, Zahra Poursalehi, Negin Hosseini Rouzbahani, Sohaib Mohammadyar, Mohammad Vasei* ORCID
Bioimpacts. 2024;14(6): 30087. doi: 10.34172/bi.2024.30087
PMCID: PMC11530967     PMID: 39493894     Scopus ID: 85209235663    
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5. The promise of gene therapy in common types of dementia
Mojtaba Ghobadi ORCID, Mohammad Foad Heidari, Arezoo Farhadi, Ali Shakerimoghaddam, Mahdi Ghorbani, Zahra Hami, Naeim Ehtesham, Javad Behroozi* ORCID
Bioimpacts. 2025;15: 30795 | Published on: 2025 Apr 21. doi: 10.34172/bi.30795
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As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate (2024): 20% 
Publication fee: Free of charge

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