Zahra Shokravi, Laleh Mehrad, Ali Ramazani*
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Maryam Moazeni , Majid Saeedi , Hamidreza Kelidari , Behrad Roohi, Mohammad T Hedayati , Tahereh Shokohi , Mojtaba Nabili , Kofi Asare-Addo , Ali Nokhodchi*
Due to the occurrence of fluconazole resistance to Candida glabrata, four resistant as well as one standard isolates were exposed to fluconazole loaded nanostructured lipid carrier alongside conventional fluconazole. These data represent the possible changes in efflux pumps genes expression.
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Aleksandr L. Urakov* , Natalya A. Urakova
Aleksandr Urakov is a professor, head of the department of General and Clinical Pharmacology at the Izhevsk State Medical Academy (ISMA). His specific research interest is in physical-chemical materials science, pharmacy, and medicine to develop new inventions designed to diagnose, prevent, and treat life-threatening conditions.
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Niloofar Babanejad , Umadevi Kandalam, Yadollah Omidi , Hamid Omidian*
MG63 and GMS Cell exposure to the control PEO and melted PEO (80°C-treated samples) demonstrated no cell toxicity, however cell exposure to 180°C-treated samples exhibited severe cell toxicity that is attributed to the byproducts remained of the PEO thermo-oxidative degradation. Cytotoxicity of the manipulated PEO is independent of its molecular weight.
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Yalda Rahbar Saadat , Jaleh Barar*
Jaleh Barar (PharmD, Ph.D.) is a Full Professor at the Faculty of Pharmacy, Tabriz University of Medical Sciences. Professor Barar is working on various aspects of pharmaceutical cell biology with particular emphasis on the development of novel drug delivery/targeting systems. Dr Barar is listed among top 1% of world scientists based on ESI ranking system.
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Yuri Yu. Shchegolev , Danila V. Sorokin, Alexander M. Scherbakov* , Olga E. Andreeva , Diana I. Salnikova , Ekaterina I. Mikhaevich , Margarita V. Gudkova , Mikhail A. Krasil’nikov
Prolonged cell treatment with mTOR inhibitor rapamycin leads to the development of resistance. Exosomes of resistant cells induce the resistance to rapamycin in the parent MCF-7cells. Exosome-induced resistance reproduces the changes revealed in the rapamycin-resistant cells, including the activation of ERK/AP-1.
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Mostafa Akbarzadeh-Khiavi , Azam Safary , Yadollah Omidi*
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