Hassan Rasouli, Amir Hossein Norooznezhad, Tahereh Rashidi, Zohreh Hoseinkhani, Azadeh Mahnam, Mitra Tarlan, Narges Moasefi, Ali Mostafaei*, Kamran Mansouri*
|
Amir Shakouri  , Houman Kahroba, Hamed Hamishekar, Jalal Abdolalizadeh*
In the first stage of the procedure, medical leech saliva was extracted and for encapsulating these proteins, liposome technique was applied. Continually, nano drug applied on cancer cells and expression of genes were evaluated by Real- Time PCR and western blotting.
|
Sanaz Javanmardi , Samira Sadat Abolmaali* , Mohammad Javad Mehrabanpour, Mahmoud Reza Aghamaali, Ali Mohammad Tamaddon
miR-21 overexpression can result in down-regulation of the critical inhibitory proteins in tumor cells. Anti-miR-21 delivery to resistant ovary tumor cells using the carboxymethylated PEG5k-polyethylenemine nanohydrogels bearing redox-sensitive crosslinks, knockdown the tumor associated angiogenesis and provoke apoptosis though ROS generation.
|
Sepideh Sheshpari , Mahnaz Shahnazi, Shahin Ahmadian, Mohammad Nouri, Mehran Mesgari Abbasi, Rahim Beheshti, Reza Rahbarghazi, Ali Honaramooz, Mahdi Mahdipour*
The administration of c-Kit+ cells can modulate angiogenesis and pathological changes, leading to the rejuvenation of ovarian function of a rat model of premature menopause.
|
Mohammad Hasan Soheilifar , Majid Pornour , Massoud Saidijam, Rezvan Najafi, Farid Azizi Jalilian, Hoda Keshmiri Neghab, Razieh Amini*
MiR-1290 through suppression of THBS1 and DKK3 could activate PI3K/AKT pathway. Moreover, DKK3 and SCAI inhibition might induce wnt/β-catenin signaling pathway. Hence, regulatory interplay between miR-1290 and its targets may promote oncogenesis and angiogenesis in CRC through PI3K/AKT and Wnt/ β-catenin signaling pathways activation.
|
Nahideh Nazdikbin Yamchi , Farhad Amjadi, Rahim Beheshti, Mehdi Hassanpour, Reza Shirazi, Amin Tamadon , Reza Rahbarghazi , Mahdi Mahdipour*
|