Wael A. Mahdi  , Mohammad S. Absar, Suna Choi, Victor C. Yang, Young M. Kwon*
The tPA was successfully modified via enzymatic oxidation by GO, resulting in enhanced control of its activity in the prodrug construct. This approach can be applied to other therapeutic glycoproteins.
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Raja Rajeswari Rajeshkumar , Banoth Karan Kumar , Pavadai Parasuraman , Theivendren Panneerselvam , Krishnan Sundar , Damodar Nayak Ammunje , Sureshbabu Ram Kumar Pandian , Sankaranarayanan Murugesan , Shanmugampillai Jeyarajaguru Kabilan , Selvaraj Kunjiappan*
The bioactive compounds from Cynodon dactylon potentially degrade the α-Syn aggregation in the brain through in silico molecular docking investigations. A molecular dynamics simulation confirms the stability of the α-Syn-ligand complex.
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Fatima Molavi , Mohammad Barzegar-Jalali , Hamed Hamishehkar*
Evaluation of different variables on preparation of Microspheres. F9; Freeze-dried particles prepared by W/O/W emulsion method, F1; Dried particles on the tray at room temperature, F16; Freeze-dried particles prepared by S/O/O emulsion method. W/O/W; Water in oil in water, S/O/O; Solid in oil in oil.
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Laura Cabeza , Mazen M. El-Hammadi , Raul Ortiz , Maria D. Cayero-Otero, Julia Jiménez-López , Gloria Perazzoli , Lucia Martin-Banderas , Jose M. Baeyens , Consolación Melguizo* , Jose Prados
These results suggest that our PTX-PLGA NPs could be a suitable strategy for breast cancer therapy, improving antitumor drug efficiency and reducing systemic toxicity without altering its mechanism of action.
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Vahid Ghafouri* , Majid Badieirostami, Morteza Fathipour
Schematic of the microfluidic device, top view and cross section of the middle part of the microfluidic device, tumor cell labeled with the functionalized antibodies with the Fe3O4 PMNPs, surface functionalization of the Si nanowires, SEM images of the middle part of the Si substrate with well-aligned SiNWs, SEM images of the tilted view of cancer cells trapped on the nanowires substrate microfluidic channel.
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Nasrollah Jabbari , Maryam Feghhi, Omid Esnaashari, Hamid Soraya, Jafar Rezaie*
Treatment of MCF-10a, MCF-7, and MDA-MD-231 cells with Gallic acid resulted in inhibition in the activity of the exosomal secretory pathway. Gallic acid can decrease the expression of genes involved in exosomes biogenesis (Alix and CD63) and secretion (Rab proteins). In addition, Gallic acid can change the expression of autophagy markers (LC3 and P62) in these cells. MVB: multivesicular body.
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Maryam Moazeni , Majid Saeedi , Hamidreza Kelidari , Behrad Roohi, Mohammad T Hedayati , Tahereh Shokohi , Mojtaba Nabili , Kofi Asare-Addo , Ali Nokhodchi*
Due to the occurrence of fluconazole resistance to Candida glabrata, four resistant as well as one standard isolates were exposed to fluconazole loaded nanostructured lipid carrier alongside conventional fluconazole. These data represent the possible changes in efflux pumps genes expression.
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Alireza Khoshroo* , Maryamosadat Mavaei, Masoume Rostami, Bahare Valinezhad-Saghezi, Ali Fattahi*
This review presents an overview of different recognition elements on an electrochemical platform for the detection of bacteria.
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Fatemeh Khonsari , Mostafa Heydari , Rassoul Dinarvand , Mohammad Sharifzadeh , Fatemeh Atyabi*
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