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Editorial
Mostafa Akbarzadeh Khiavi ORCID, Azam Safary ORCID, Mohammad Hossein Somi* ORCID
Bioimpacts. 2019;9(3): 123-127. doi: 10.15171/bi.2019.16
PMCID: PMC6726747     PMID: 31508327     Scopus ID: 85071177336    
Colorectal cancer (CRC) as a malignancy shows high mortality rate worldwide because of metastasis and drug resistance. Targeted multimodal nanosystems (NSs) can be developed and used against CRC with much better clinical outcomes.

Editorial
Morteza Mahmoudi* ORCID
Bioimpacts. 2019;9(3): 129-130. doi: 10.15171/bi.2019.17
PMCID: PMC6726746     PMID: 31508328     Scopus ID: 85071177336     WOS: 000483926500002    
Scientific bullying, as a growing concern, may emerge differently (from insults/snubs to violations of intellectual properties). Strategies such as specific training and detailed examination might be helpful for those at risk of bullying.

Original Research
Mohammad Mostafa Pourseif, Mitra Yousefpour*, Mohammad Aminianfar, Gholamali Moghaddam, Ahmad Nematollahi ORCID
Bioimpacts. 2019;9(3): 131-144. doi: 10.15171/bi.2019.18
PMCID: PMC6726745     PMID: 31508329     Scopus ID: 85071191509     WOS: 000483926500003    
The minigene vaccine construct is designed based on the B and T cell epitopes of E. granulosus enolase protein, and ligands for TLR-2 and TLR-4. The minigene vaccine showed stable properties for proper binding with the Toll-like receptors.

Original Research
Mohammad Reza Asgharzadeh, Mohammad M. Pourseif, Jaleh Barar ORCID, Morteza Eskandani, Mojtaba Jafari Niya, Mohammad Reza Mashayekhi, Yadollah Omidi* ORCID
Bioimpacts. 2019;9(3): 145-159. doi: 10.15171/bi.2019.19
PMCID: PMC6726749     PMID: 31508330     Scopus ID: 85071154393     WOS: 000483926500004    
Increased expression of TSGA10 associated with the reduced metastasis in the MDA-MB-231 cells. TSGA10 showed interaction with HIF-1α with high affinity. TSGA10 expression is altered under the hypoxia, indicating its potential as a bio-target for cancer therapy.

Original Research
Stephan Born*, Max Johannes Dörfel, Philip Hartjen, Seyed Ali Haschemi Yekani, Julia Luecke, Juliane Katharina Meutsch, Julie Katharina Westphal, Moritz Birkelbach, Robert Köhnke, Ralf Smeets, Michael Krueger
Bioimpacts. 2019;9(3): 161-172. doi: 10.15171/bi.2019.20
PMCID: PMC6726751     PMID: 31508331     Scopus ID: 85071165666     WOS: 000483926500005    
The purification process for stromal vascular fraction (SVF) can be performed using additional short plastic adherence incubation step (16-20h). This process leads in 24h to a predictable GMP-compliant cell-product. This product is more homogenous than the SVF.

Original Research
Yalda Salari Lak ORCID, Sirous Khorram ORCID, Mehran Mesgari Abbasi ORCID, Mohammad Asghari-Jafarabadi ORCID, Ali Tarighat-Esfanjani* ORCID, Elahe Bazri ORCID, Hossein Omidi ORCID
Bioimpacts. 2019;9(3): 173-178. doi: 10.15171/bi.2019.21
PMCID: PMC6726750     PMID: 31508332     Scopus ID: 85071196278     WOS: 000483926500006    
Supplementation with Nigella Sativa and nano-sized clinoptilolite in rats with diabetes mellitusinduced with high-fat diet and injection of 35 mg/kg BW of streptozotocin, resulted in asignificant increase in calcium, alkaline phosphatase, and parathyroid hormone levels.

Original Research
Khosro Adibkia ORCID, Sevil Selselehjonban ORCID, Shahram Emami ORCID, Karim Osouli-Bostanabad ORCID, Mohammad Barzegar-Jalali* ORCID
Bioimpacts. 2019;9(3): 179-188. doi: 10.15171/bi.2019.22
PMCID: PMC6726752     PMID: 31508333     Scopus ID: 85071146642     WOS: 000483926500007    
Electrospraying of modafinil and Eudragit RS100 using different drug: polymer ratios and various solution concentrations can lead to the formation of unique nanostructures such as nonobeads and nanofibers depending on the polymer concentration in the feed solution.

Short Communication
Saeed Khamnei, Seyyed-Reza Sadat-Ebrahimi, Shaker Salarilak, Siavash Savadi Oskoee, Yousef Houshyar, Seyed Kazem Shakouri, Yaghoub Salekzamani, Masumeh Zamanlu*
Bioimpacts. 2019;9(3): 189-193. doi: 10.15171/bi.2019.23
PMCID: PMC6726748     PMID: 31508334     Scopus ID: 85071147871     WOS: 000483926500008    

Two lateralities in the same side considerably might imply the solidarity in the control of the dominant brain hemisphere, while the unilaterality appears to be more prominent. Thus, masticatory preference is found with probable origins in the dominant hemisphere of the brain.