Ailar Nakhlband, Jaleh Barar*
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Jaleh Barar* , Yadollah Omidi*
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Yadollah Omidi , Jaleh Barar*
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Omid Mashinchian, Mohammad Johari-Ahar, Behnaz Ghaemi, Mohammad Rashidi, Jaleh Barar* , Yadollah Omidi*
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Jaleh Barar*
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Mohammad-Hossein Biglu*, Shukuh Riazi
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Yadollah Omidi*
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Yadollah Omidi*
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Yadollah Omidi* , Jaleh Barar
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Jaleh Barar , Yadollah Omidi*
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Marziyeh Fathi, Parham Sahandi Zangabad, Sima Majidi, Jaleh Barar, Hamid Erfan-Niya, Yadollah Omidi*
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Ailar Nakhlband, Morteza Eskandani, Yadollah Omidi , Nazli Saeedi, Samad Ghafari, Jaleh Barar* , Alireza Garjani*
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Ayuob Aghanejad, Hiwa Babamiri, Khosro Adibkia, Jaleh Barar , Yadollah Omidi*
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Somayeh Vandghanooni, Morteza Eskandani, Jaleh Barar , Yadollah Omidi*
Aptamers (Aps) are short single-strand nucleic acids, which can be used as the therapeutic and targeting agent in advanced drug delivery systems. Conjugation of Aps with other entities (siRNA, toxins, drugs, DNAzyme/Ribozymes) provides advanced multifunctional nanosystems for cancer therapy.
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Mostafa Akbarzadeh Khiavi , Azam Safary , Mohammad Hossein Somi*
Colorectal cancer (CRC) as a malignancy shows high mortality rate worldwide because of metastasis and drug resistance. Targeted multimodal nanosystems (NSs) can be developed and used against CRC with much better clinical outcomes.
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Mostafa Akbarzadeh Khiavi , Azam Safary , Jaleh Barar , Hamed Farzi-Khajeh, Abolfazl Barzegari, Rahimeh Mousavi, Mohammad Hossein Somi* , Yadollah Omidi*
The current study introduces an efficient ROS-responsive enzyme-based nanobiosystem and its biological impact in colon cancer therapy. Based on physicochemical properties, AuNPs-PEG-RNase A effectively induced apoptosis in SW-480 colon cancer cells and resulted in a significant reduction in cancer cell viability.
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Jaleh Barar*
The vast knowledge about the pathways that regulate the virus entry and molecular signaling of the pathogenesis of coronavirus are the key factor for the development of de novo nanoscaled diagnostic/therapeutic strategies.
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Efthymia-Iliana Matthaiou , Yi Guo, Jaleh Barar , Raphael Sandaltzopoulos, Lana E. Kandalaft, Chunsheng Li*, George Coukos, Yadollah Omidi*
Poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) functionalized with polyethylene glycol (PEG)and anti-TEM1 antibody fragment (78Fc) and loaded with necrosis-inducing agent shikonin (SHK)(78Fc-PLGA-SHK NPs) is a highly effective immunostimulating nanomedicine against theTEM1-expressing cells for targeted therapy of solid tumors.
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Nazanin Kianinejad , Young Min Kwon*
Young M. Kwon is an associate professor of Pharmaceutical Sciences at Nova Southeastern University, College of Pharmacy (USA). Dr. Kwon’s research interests include targeted delivery and controlled release of biological molecules.
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